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  1. Transcription

    transcription, the synthesis of RNA from DNA.Genetic information flows from DNA into protein, the substance that gives an organism its form.This flow of information occurs through the sequential processes of transcription (DNA to RNA) and translation (RNA to protein). Transcription occurs when there is a need for a particular gene product at a specific time or in a specific tissue.

  2. Transcription: an overview of DNA transcription (article)

    Transcription is the first step in gene expression. It involves copying a gene's DNA sequence to make an RNA molecule. Transcription is performed by enzymes called RNA polymerases, which link nucleotides to form an RNA strand (using a DNA strand as a template). Transcription has three stages: initiation, elongation, and termination.

  3. Stages of transcription

    Transcription overview. Transcription is the first step of gene expression. During this process, the DNA sequence of a gene is copied into RNA. Before transcription can take place, the DNA double helix must unwind near the gene that is getting transcribed. The region of opened-up DNA is called a transcription bubble.

  4. Transcription (biology)

    Transcription is the process of copying a segment of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins produce messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding RNAs (ncRNAs).. Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language.

  5. 9.3: Transcription

    Figure 9.3.1 9.3. 1: The central dogma states that DNA encodes RNA, which in turn encodes protein. The copying of DNA to mRNA is relatively straightforward, with one nucleotide being added to the mRNA strand for every complementary nucleotide read in the DNA strand. The translation to protein is more complex because groups of three mRNA ...

  6. Transcription: the epicenter of gene expression

    Transcription: the epicenter of gene expression. The complexity of a living organism is not driven by gene number but gene regulation. Controlling which genes to express and to what extent dictates the subsequent cell identity. Transcription, the critical initial stage in gene expression, is regulated delicately to maintain the cell status.

  7. 9.3 Transcription

    Elongation. Transcription always proceeds from one of the two DNA strands, which is called the template strand.The mRNA product is complementary to the template strand and is almost identical to the other DNA strand, called the nontemplate strand, with the exception that RNA contains a uracil (U) in place of the thymine (T) found in DNA.During elongation, an enzyme called RNA polymerase ...

  8. DNA Transcription

    The first step in transcription is initiation, when the RNA pol binds to the DNA upstream (5′) of the gene at a specialized sequence called a promoter (Figure 2a). In bacteria, promoters are ...

  9. transcription / DNA transcription

    Transcription is the process by which the information in a strand of DNA is copied into a new molecule of messenger RNA (mRNA). DNA safely and stably stores genetic material in the nuclei of cells ...

  10. 7.5: Transcription

    Transcription by RNA polymerase II requires the general transcription factors and the RNA polymerase to form a complex, at the TATA box, called the basal transcription complex or transcription initiation complex (Figure 7.65). This is the minimum requirement for any gene to be transcribed. The first step in the formation of this complex is the ...

  11. 10.3: Steps of Transcription

    During transcription, a strand of mRNA is made that is complementary to a strand of DNA. Figure 1 shows how this occurs. Eventually portions of the transcribed mRNA will be made into functional proteins. Figure 1. Overview of Transcription. Transcription uses the sequence of bases in a strand of DNA to make a complementary strand of mRNA.

  12. 15.3 Eukaryotic Transcription

    Basal transcription factors are crucial in the formation of a preinitiation complex on the DNA template that subsequently recruits RNA polymerase II for transcription initiation. The names of the basal transcription factors begin with "TFII" (this is the transcription factor for RNA polymerase II) and are specified with the letters A-J.

  13. Transcription

    Transcription Definition. Transcription refers to the first step of gene expression where an RNA polymer is created from a DNA template. This reaction is catalyzed by enzymes called RNA polymerases and the RNA polymer is antiparallel and complementary to the DNA template. The stretch of DNA that codes for an RNA transcript is called a ...

  14. DNA replication and RNA transcription and translation

    Transcript. DNA serves as the molecular basis of heredity through replication, expression, and translation processes. Replication creates identical DNA strands, while transcription converts DNA into messenger RNA (mRNA). Translation then decodes mRNA into amino acids, forming proteins essential for life functions. Created by Sal Khan.

  15. Steps of Transcription

    Step 1: Initiation. Initiation is the beginning of transcription. It occurs when the enzyme RNA polymerase binds to a region of a gene called the promoter. This signals the DNA to unwind so the enzyme can ''read'' the bases in one of the DNA strands. The enzyme is now ready to make a strand of mRNA with a complementary sequence of bases.

  16. Transcription (biology) Definition and Examples

    Transcription is a biological process wherein the mRNA transcript (i.e. a copy of the coding sequence for a particular protein) is produced, generally by transcribing the template strand of the DNA.This transcript serves as a template for the next step of protein biosynthesis, translation, through the help of the enzyme, RNA polymerase.Thus, transcription is regarded as the first step of gene ...

  17. 10.2: Overview of Transcription

    By convention, upstream refers to DNA 5' to a given reference point on the DNA (e.g., the transcription start-site of a gene). Downstream then, refers to DNA 3' to a given reference point on the DNA. 188 Transcription Overview: The Basic Mechanism of RNA Synthesis. In bacteria, some transcription units encode more than one kind of RNA.

  18. Transcription ( Read )

    Transcription is the DNA → RNA part of the central dogma of molecular biology. Transcription occurs in the nucleus of eukaryotic cells. During transcription, a copy of mRNA is made that is complementary to a strand of DNA. In eukaryotes, mRNA may be modified before it leaves the nucleus of eukaryotic cells. .

  19. Transcription and Translation

    Transcription uses a strand of DNA as a template to build a molecule called RNA. The RNA molecule is the link between DNA and the production of proteins. During translation, the RNA molecule created in the transcription process delivers information from the DNA to the protein-building machines. DNA → RNA → Protein

  20. What Is Transcription?

    The RNA polymerase is the main enzyme involved in transcription. It uses single-strand DNA to synthesize a complementary RNA strand. The DNA-dependent RNA polymerase binds to the promoter and catalyses the polymerization in the 5' to 3' direction on the template strand. Once it reaches the terminator sequence, the process terminates and the ...

  21. Transcription and Translation

    This biology video tutorial provides a basic introduction into transcription and translation which explains protein synthesis starting from DNA. Transcripti...

  22. Transcription directionality is licensed by Integrator at ...

    However, how the transcription machinery selects the correct direction to produce pre-mRNAs is largely unknown. ... ChromRNA-seq libraries were quantified with a Bio-Fragment Analyzer (Bioptic ...

  23. 8.1: Introduction to Transcription

    The process of copying DNA into RNA is called transcription. In both prokaryotes and eukaryotes, transcription requires certain control elements (sequences of nucleotides within the DNA) to proceed properly. These elements are a promoter, a start site, and a stop site. The need for a recognizable point to begin and a point to end the process is ...

  24. Integrative Data Analysis to Uncover Transcription Factors ...

    Finally, for each transcription factor, we used a statistical test to assess whether the credible SNPs show enrichments in terms of changing the binding probability of that transcription factor at multiple sites. Our analysis resulted in identification of significantly enriched transcription factors and their relevant cell types for each trait.

  25. In-vitro Transcription Templates Market Expected to Grow at ...

    Global In-vitro Transcription Templates Market is valued at US$ 277.57 Mn in 2023, and it is expected to reach US$ 1,134.1 Mn by 2031, with a CAGR of 19.5% during the forecast period of 2024-2031.. Market Analysis: In-vitro transcription is a laboratory scientific method to produce RNA molecules from a DNA template in a controlled environment, separate from a living cell.

  26. Lecture 18: Transcription

    Promoters. Proteins responsible for creating an RNA copy of a specific piece of DNA (transcription) must first be able to recognize the beginning of the element to be copied. A promoter is a DNA sequence onto which various proteins, collectively known as the transcription machinery, bind and initiates transcription.

  27. Overexpression of the WRKY transcription factor gene

    Background Salt stress severely inhibits plant growth, and the WRKY family transcription factors play important roles in salt stress resistance. In this study, we aimed to characterize the role of tobacco (Nicotiana tabacum) NtWRKY65 transcription factor gene in salinity tolerance. Results This study characterized the role of tobacco (Nicotiana tabacum) NtWRKY65 transcription factor gene in ...