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Microbiology and Molecular Biology Theses and Dissertations

Theses/dissertations from 2024 2024.

Characterization of Cellular Metabolism Regulation by the Transcription Factor Centromere Binding Factor 1 (Cbf1) , Spencer Ellsworth

Theses/Dissertations from 2023 2023

Elucidating the Architecture of the TclIJN Complex that Converts Cysteine to Thiazoles in the Biosynthesis of Micrococcin , Diana G. Calvopina Chavez

Manipulating and Assaying Chromatin Architecture Around Enhancer Elements in vivo , John Lawrence Carter

Halophilic Genes that Impact Plant Growth in Saline Soils , Mckay A. Meinzer

Characterizing Stress Granule Regulation by PAS Kinase, Ataxin-2 and Ptc6 and Investigating the Lifespan of Covid-19 Virus on Currency , Colleen R. Newey

Changes in RNA Expression of HuT78 Cells Resulting From the HIV-1 Viral Protein R R77Q Mutation , Joshua S. Ramsey

Theses/Dissertations from 2022 2022

Biofilm Characterization and the Potential Role of eDNA in Horizontal Gene Transfer in Hospital and Meat Isolates of Staphylococcus aureus and Their Biofilms , Ashley Lynne Ball

Novel Patterns for Nucleosome Positioning: From in vitro to in vivo , David Andrew Bates

The Effects of Polymorphisms of Viral Protein R of HIV-1 on the Induction of Apoptosis in Primary Cells and the Characterization of Twelve Novel Bacillus anthracis Bacteriophage , Jacob D. Fairholm

Analysis of the Cytopathogenic Effect of Different HIV-1 Vpr Isoforms on Primary Human CD4+ T Cells and a Model Cell Line , Jonatan Josue Fierro Nieves

The Role of Chitinase A in Mastitis-Associated Escherichia coli Pathogenesis , Weston D. Hutchison

Big Data Meta-Analyses of Transcriptional Responses of Human Samples to Orthohantavirus Infection and Shotgun Metagenomics From Crohn's Disease Patients. , John L. Krapohl

An Exploration of Factors that Impact Uptake of Human Papillomavirus Vaccines , David Samuel Redd

Genomic Analysis and Therapeutic Development of Bacteriophages to Treat Bacterial Infections and Parasitic Infestations , Daniel W. Thompson

The Use of Nucleotide Salvage Pathway Enzymes as Suitable Tumor Targets for Antibody-Based and Adoptive Cell Therapies , Edwin J. Velazquez

Comparative Sequence Analysis Elucidates the Evolutionary Patterns of Yersinia pestis in New Mexico over Thirty-Two Years , M. Elizabeth Warren

Regulation of T Cell Activation by the CD5 Co-Receptor and Altered Peptides, Characterization of Thymidine Kinase-Specific Antibodies, and Integrating Genomics Education in Society , Kiara Vaden Whitley

Theses/Dissertations from 2021 2021

Evolution and Selection: From Suppression of Metabolic Deficiencies to Bacteriophage Host Range and Resistance , Daniel Kurt Arens

Identifying Sinorhizobium meliloti Genes that Determine Fitness Outcomes , Alexander B. Benedict

Pushing the Limits of SARS-CoV-2 Survival: How SARS-CoV-2 Responds to Quaternary Ammonium Compounds and Wastewater , Benjamin Hawthorne Ogilvie

Mutations in HIV-1 Vpr Affect Pathogenesis in T-Lymphocytes and Novel Strategies to Contain the Current COVID-19 Pandemic , Antonio Solis Leal

Theses/Dissertations from 2020 2020

Staphylococcus aureus Metal Acquisition in Milk and Mammary Gland Tissue , Shalee Killpack Carlson

Antimicrobial Peptide Development: From Massively Parallel Peptide Sequencing to Bioinformatic Motif Identification , Alexander K. Erikson

A Comparison of Chikungunya Virus Infection, Dissemination, and Cytokine Induction in Human and Murine Macrophages and Characterization of RAG2-/-γc-/- Mice as an Animal Model to Study Neurotropic Chikungunya Disease , Israel Guerrero

The Effects of Immune Regulation and Dysregulation: Helper T Cell Receptor Affinity, Systemic Lupus Erythematosus and Cancer Risk, and Vaccine Hesitancy , Deborah K. Johnson

Identification of Genes that Determine Fitness, Virulence, and Disease Outcomes in Mastitis Associated Eschericia coli , Michael Andrew Olson

Theses/Dissertations from 2019 2019

Investigation of Thymidine Kinase 1 in Cancer Progression , Eliza Esther King Bitter

Ribosomally Synthesized and Post-Translationally Modified Peptides as Potential Scaffolds for Peptide Engineering , Devan Bursey

Bioaerosols Associated with Evaporative Cooler Use in Low-Income Homes in Semi-Arid Climates , Ashlin Elaine Cowger

PAS Kinase and TOR, Controllers of Cell Growth and Proliferation , Brooke Jasmyn Cozzens

Regulation of Immune Cell Activation and Functionby the nBMPp2 Protein andthe CD5 Co-Receptor , Claudia Mercedes Freitas

Characterizing Novel Pathways for Regulation and Function of Ataxin-2 , Elise Spencer Melhado

Interactions Between the Organellar Pol1A, Pol1B, and Twinkle DNA Replication Proteins and Their Role in Plant Organelle DNA Replication , Stewart Anthony Morley

SNFing Glucose to PASs Mitochondrial Dysfunction: The Role of Two Sensory Protein Kinases in Metabolic Diseases , Kai Li Ong

Characterizing the Function of PAS kinase in Cellular Metabolism and Neurodegenerative Disease , Jenny Adele Pape

Isolation, Characterization, and Genomic Comparison of Bacteriophages of Enterobacteriales Order , Ruchira Sharma

Isolation, Genetic Characterization and Clinical Application of Bacteriophages of Pathogenic Bacterial Species , Trever Leon Thurgood

Investigation of Therapeutic Immune Cell Metabolism , Josephine Anna Tueller

Theses/Dissertations from 2018 2018

Innate Immune Cell Phenotypes Are Dictated by Distinct Epigenetic Reprogramming , Kevin Douglas Adams

Bacteriophages for Treating American Foulbrood and the Neutralization of Paenibacillus larvae Spores , Thomas Scott Brady

Methods for Detection of and Therapy for Carbapenem-Resistant Enterobacteriaceae , Olivia Tateoka Brown

The Diversity Found Among Carbapenem-Resistant Bacteria , Galen Edward Card

Exploration of Antimicrobial Activity in Natural Peptides and High-Throughput Discovery of Synthetic Peptides , Emma Kay Dallon

Gut Microbiota Regulates the Interplay Between Diet and Genetics to Influence Insulin Resistance , Jeralyn Jones Franson

The Antimicrobial Properties of Honey and Their Effect on Pathogenic Bacteria , Shreena Himanshu Mody

The Ability of Novel Phage to Infect Virulent Bacillus anthracis Isolates , Hyrum Smith Shumway

Galleria Mellonella as an Alternate Infection Model for Burkholderia Species and a Comparison of Suspension and Surface Test Methods for Evaluating Sporicidal Efficacy , Joseph D. Thiriot

The Clinical Significance of HPRT as a Diagnostic and Therapeutic Biomarker for Hematological and Solid Malignancies , Michelle Hannah Townsend

Biomarker Analysis and Clinical Relevance of Thymidine Kinase 1 in Solid and Hematological Malignancies , Evita Giraldez Weagel

Hospital and meat associated Staphylococcus aureus and Their Biofilm Characteristics , Trevor Michael Wienclaw

Theses/Dissertations from 2017 2017

Comparison of Cytokine Expression and Bacterial Growth During Periparturient and Mid Lactation Mastitis in a Mouse Model , Rhonda Nicole Chronis

Influence of Epstein-Barr Virus on Systemic Lupus Erythematosus Disease Development and the Role of Depression on Disease Progression , Caleb Cornaby

The Effects of Nucleosome Positioning and Chromatin Architecture on Transgene Expression , Colton E. Kempton

Phosphate Signaling Through Alternate Conformations of the PstSCAB Phosphate Transporter , Ramesh Krishna Vuppada

Acetobacter fabarum Genes Influencing Drosophila melanogaster Phenotypes , Kylie MaKay White

Theses/Dissertations from 2016 2016

The Path to Understanding Salt Tolerance: Global Profiling of Genes Using Transcriptomics of the Halophyte Suaeda fruticosa , Joann Diray Arce

Genetic and Biochemical Analysis of the Micrococcin Biosynthetic Pathway , Philip Ross Bennallack

Characterizing Interaction Between PASK and PBP1/ ATXN2 to Regulate Cell Growth and Proliferation , Nidhi Rajan Choksi

The Activity of Alkaline Glutaraldehyde Against Bacterial Endospores and Select Non-Enveloped Viruses , Justen Thalmus Despain

The Role of Viral Interleukin-6 in Tumor Development of Kaposi's Sarcoma-Associated Herpesvirus Lymphomas , Rebecca A. Fullwood

The Role of the Transcriptional Antiterminator RfaH in Lipopolysaccharide Synthesis, Resistance to Antimicrobial Peptides, and Virulence of Yersinia pseudotuberculosis and Yersinia pestis , Jared Michael Hoffman

A CryAB Interactome Reveals Clientele Specificity and Dysfunction of Mutants Associated with Human Disease , Whitney Katherine Hoopes

The pmrHFIJKLM Operon in Yersinia pseudotuberculosis Enhances Resistance to CCL28 and Promotes Phagocytic Engulfment by Neutrophils , Lauren Elizabeth Johnson

Characterization of Five Brevibacillus Bacteriophages and Their Genomes , Michael Allen Sheflo

Analysis of Nucleosome Isolation and Recovery: From In Silico Invitrosomes to In Vivo Nucleosomes , Collin Brendan Skousen

Human Herpesvirus 6A Infection and Immunopathogenesis in Humanized Rag2 -/-γc-/- Mice and Relevance to HIV/AIDS and Autoimmunity , Anne Tanner

Theses/Dissertations from 2015 2015

Identifying and Characterizing Yeast PAS Kinase 1 Substrates Reveals Regulation of Mitochondrial and Cell Growth Pathways , Desiree DeMille

The Detection and Molecular Evolution of Francisella tularensis Subspecies , Mark K. Gunnell

Isolation and Host Range of Staphylococcus aureus Bacteriophages and Use for Decontamination of Fomites , Kyle C. Jensen

The Antioxidant and DNA Repair Capacities of Resveratrol, Piceatannol, and Pterostilbene , Justin Ryan Livingston

High Salinity Stabilizes Bacterial Community Composition and Activity Through Time , Tylan Wayne Magnusson

Advancing Phage Genomics and Honeybee Health Through Discovery and Characterization of Paenibacillaceae Bacteriophages , Bryan Douglas Merrill

Specialized Replication Operons Control Rhizobial Plasmid Copy Number in Developing Symbiotic Cells , Clarice Lorraine Perry

Gene Networks Involved in Competitive Root Colonization and Nodulation in the Sinorhizobium meliloti-Medicago truncatula Symbiosis , Ryan D. VanYperen

Theses/Dissertations from 2014 2014

Snf1 Mediated Phosphorylation and Activation of PAS Kinase , Bryan D. Badal

Studies of PhoU in Escherichia coli: Metal Binding, Dimerization,Protein/Protein Interactions, and a Signaling Complex Model , Stewart G. Gardner

Pharmacologic Immunomodulation of Macrophage Activation by Caffeine , Ryan Perry Steck

Analysis of Nucleosome Mobility, Fragility, and Recovery: From Embryonic Stem Cells to Invitrosomes , Ashley Nicolle Wright

Enhancing Protein and Enzyme Stability Through Rationally Engineered Site-Specific Immobilization Utilizing Non-Canonical Amino Acids , Jeffrey Chun Wu

Theses/Dissertations from 2013 2013

Thymidine Kinase 1: Diagnostic and Prognostic Significance in Malignancy , Melissa Marie Alegre

Promoter Polymorphisms in Interferon Regulatory Factor 5 , Daniel N. Clark

Modulators of Symbiotic Outcome in Sinorhizobium meliloti , Matthew B. Crook

Evidences for Protein-Protein Interactions Between PstB and PhoU in the Phosphate Signaling Complex of Escherichia coli , Kristine Dawn Johns

Identification of the Binding Partners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactions and Non-Redundant Roles for Small Heat Shock Proteins , Kelsey Murphey Langston

A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Burkholderia pseudomallei Complex: B. mallei , B. pseudomallei , and B. thailandensis , Chinn-woan Lowe

The Role of Nuclear BMP2 in the Cell Cycle and Tumorigenesis , Brandt Alan Nichols

Nuclear BMP2 and the Immune Response , Daniel S. Olsen

Hypersaline Lake Environments Exhibit Reduced Microbial Dormancy , Joshua Christopher Vert

Theses/Dissertations from 2012 2012

Characterization of the Cellular and Organellar Dynamics that Occur with a Partial Depletion of Mitochondrial DNA when Arabidopsis Organellar DNA Polymerase IB is Mutated , John D. Cupp

Effect of Antioxidants and Oxidative Stress on Different Cancer Cell Types , Gaytri Devi Gupta Elera

Effects of Chemical Stimulation and Tumor Co-Incubation on Macrophage Activation and Aggressiveness, Measured Through Phagocytosis and Respiratory Burst , Bo Marcus Gustafsson

Loss of the Lipopolysaccharide Core Biosynthesis rfaD Gene Increases Antimicrobial Chemokine Binding and Bacterial Susceptibility to CCL28 and Polymyxin: A Model for Understanding the Interface of Antimicrobial Chemokines and Bacterial Host Defense Avoidance Mechanisms , Cynthia S. Lew

Partial Characterization of the Antimicrobial Activity of CCL28 , Bin Liu

Characterizing the Role of HspB2 in Cardiac Metabolism and Muscle Structure Using Yeast and Mammalian Systems , Jonathan Paul Neubert

Humanized Mice as a Model to Study Human Viral Pathogenesis and Novel Antiviral Drugs , Freddy Mauricio Sanchez Tumbaco

Transgene Delivery via Microelectromechanical Systems , Aubrey Marie Mueller Wilson

Theses/Dissertations from 2011 2011

Antioxidants in Cancer Research and Prevention: Assay Comparison, Structure-Function Analysis, and Food Product Analysis , Andrew Robert Garrett

Characterization of the Role Nuclear Bmp2 (nBmp2) Plays in Regulating Gene Expression , Fialka Grigorova

Theses/Dissertations from 2010 2010

Effects of Diabetic State and Gender on Pro-Inflammatory Cytokine Secretion by Human Macrophages Infected with Burkholderia pseudomallei , Annette J. Blam

Organellar DNA Polymerases Gamma I and II in Arabidopsis thaliana , Jeffrey M. Brammer

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Digital Commons @ USF > College of Arts and Sciences > Molecular Biosciences > Theses and Dissertations

Molecular Biosciences Theses and Dissertations

Theses/dissertations from 2024 2024.

Androgen Drives Melanoma Invasiveness and Metastatic Spread by Inducing Tumorigenic Fucosylation , Qian Liu

Theses/Dissertations from 2023 2023

Exploring strain variation and bacteriophage predation in the gut microbiome of Ciona robusta , Celine Grace F. Atkinson

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression , Janine M. DeBlasi

Thermodynamic frustration of TAD2 and PRR contribute to autoinhibition of p53 , Emily Gregory

Utilization of Detonation Nanodiamonds: Nanocarrier for Gene Therapy in Non-Small Cell Lung Cancer , Allan E. Gutierrez

Role of HLA-DRB1 Fucosylation in Anti-Melanoma Immunity , Daniel K. Lester

Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML , Christopher T. Letson

Regulated Intramembrane Proteolysis by M82 Peptidases: The Role of PrsS in the Staphylococcus aureus Stress Response , Baylie M. Schott

Histone Deacetylase 8 is a Novel Therapeutic Target for Mantle Cell Lymphoma and Preserves Natural Killer Cell Cytotoxic Function , January M. Watters

Theses/Dissertations from 2022 2022

Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans , Lindsey N. Barrett

Determining the Role of Dendritic Cells During Response to Treatment with Paclitaxel/Anti-TIM-3 , Alycia Gardner

Cell-free DNA Methylation Signatures in Cancer Detection and Classification , Jinyong Huang

The Role Of Eicosanoid Metabolism in Mammalian Wound Healing and Inflammation , Kenneth D. Maus

A Holistic Investigation of Acidosis in Breast Cancer , Bryce Ordway

Characterizing the Impact of Postharvest Temperature Stress on Polyphenol Profiles of Red and White-Fruited Strawberry Cultivars , Alyssa N. Smith

Theses/Dissertations from 2021 2021

Multifaceted Approach to Understanding Acinetobacter baumannii Biofilm Formation and Drug Resistance , Jessie L. Allen

Cellular And Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology , Ravneet Kaur Chhabra

Ecology and diversity of boletes of the southeastern United States , Arian Farid

CircREV1 Expression in Triple-Negative Breast Cancer , Meagan P. Horton

Microbial Dark Matter: Culturing the Uncultured in Search of Novel Chemotaxonomy , Sarah J. Kennedy

The Multifaceted Role of CCAR-1 in the Alternative Splicing and Germline Regulation in Caenorhabditis elegans , Doreen Ikhuva Lugano

Unraveling the Role of Novel G5 Peptidase Family Proteins in Virulence and Cell Envelope Biogenesis of Staphylococcus aureus , Stephanie M. Marroquin

Cytoplasmic Polyadenylation Element Binding Protein 2 Alternative Splicing Regulates HIF1α During Chronic Hypoxia , Emily M. Mayo

Transcriptomic and Functional Investigation of Bacterial Biofilm Formation , Brooke R. Nemec

A Functional Characterization of the Omega (ω) subunit of RNA Polymerase in Staphylococcus aureus , Shrushti B. Patil

The Role Of Cpeb2 Alternative Splicing In TNBC Metastasis , Shaun C. Stevens

Screening Next-generation Fluorine-19 Probe and Preparation of Yeast-derived G Proteins for GPCR Conformation and Dynamics Study , Wenjie Zhao

Theses/Dissertations from 2020 2020

Understanding the Role of Cereblon in Hematopoiesis Through Structural and Functional Analyses , Afua Adutwumwa Akuffo

To Mid-cell and Beyond: Characterizing the Roles of GpsB and YpsA in Cell Division Regulation in Gram-positive Bacteria , Robert S. Brzozowski

Spatiotemporal Changes of Microbial Community Assemblages and Functions in the Subsurface , Madison C. Davis

New Mechanisms That Regulate DNA Double-Strand Break-Induced Gene Silencing and Genome Integrity , Dante Francis DeAscanis

Regulation of the Heat Shock Response and HSF-1 Nuclear Stress Bodies in C. elegans , Andrew Deonarine

New Mechanisms that Control FACT Histone Chaperone and Transcription-mediated Genome Stability , Angelo Vincenzo de Vivo Diaz

Targeting the ESKAPE Pathogens by Botanical and Microbial Approaches , Emily Dilandro

Succession in native groundwater microbial communities in response to effluent wastewater , Chelsea M. Dinon

Role of ceramide-1 phosphate in regulation of sphingolipid and eicosanoid metabolism in lung epithelial cells , Brittany A. Dudley

Allosteric Control of Proteins: New Methods and Mechanisms , Nalvi Duro

Microbial Community Structures in Three Bahamian Blue Holes , Meghan J. Gordon

A Novel Intramolecular Interaction in P53 , Fan He

The Impact of Myeloid-Mediated Co-Stimulation and Immunosuppression on the Anti-Tumor Efficacy of Adoptive T cell Therapy , Pasquale Patrick Innamarato

Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment , Wendy Michelle Kandell

Posttranslational Modification and Protein Disorder Regulate Protein-Protein Interactions and DNA Binding Specificity of p53 , Robin Levy

Mechanistic and Translational Studies on Skeletal Malignancies , Jeremy McGuire

Novel Long Non-Coding RNA CDLINC Promotes NSCLC Progression , Christina J. Moss

Genome Maintenance Roles of Polycomb Transcriptional Repressors BMI1 and RNF2 , Anthony Richard Sanchez IV

The Ecology and Conservation of an Urban Karst Subterranean Estuary , Robert J. Scharping

Biological and Proteomic Characterization of Cornus officinalis on Human 1.1B4 Pancreatic β Cells: Exploring Use for T1D Interventional Application , Arielle E. Tawfik

Evaluation of Aging and Genetic Mutation Variants on Tauopathy , Amber M. Tetlow

Theses/Dissertations from 2019 2019

Investigating the Proteinaceous Regulome of the Acinetobacter baumannii , Leila G. Casella

Functional Characterization of the Ovarian Tumor Domain Deubiquitinating Enzyme 6B , Jasmin M. D'Andrea

Integrated Molecular Characterization of Lung Adenocarcinoma with Implications for Immunotherapy , Nicholas T. Gimbrone

The Role of Secreted Proteases in Regulating Disease Progression in Staphylococcus aureus , Brittney D. Gimza

Advanced Proteomic and Epigenetic Characterization of Ethanol-Induced Microglial Activation , Jennifer Guergues Guergues

Understanding immunometabolic and suppressive factors that impact cancer development , Rebecca Swearingen Hesterberg

Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality , Robert T. Madden

Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia , Kamira K. Maharaj

Characterization of the Autophagic-Iron Axis in the Pathophysiology of Endometriosis and Epithelial Ovarian Cancers , Stephanie Rockfield

Understanding the Influence of the Cancer Microenvironment on Metabolism and Metastasis , Shonagh Russell

Modeling of Interaction of Ions with Ether- and Ester-linked Phospholipids , Matthew W. Saunders

Novel Insights into the Multifaceted Roles of BLM in the Maintenance of Genome Stability , Vivek M. Shastri

Conserved glycine residues control transient helicity and disorder in the cold regulated protein, Cor15a , Oluwakemi Sowemimo

A Novel Cytokine Response Modulatory Function of MEK Inhibitors Mediates Therapeutic Efficacy , Mengyu Xie

Novel Strategies on Characterizing Biologically Specific Protein-protein Interaction Networks , Bi Zhao

Theses/Dissertations from 2018 2018

Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival , Lou-Ella M.m. Alexander

Identification of Regulatory miRNAs Associated with Ethanol-Induced Microglial Activation Using Integrated Proteomic and Transcriptomic Approaches , Brandi Jo Cook

Molecular Phylogenetics of Floridian Boletes , Arian Farid

MYC Distant Enhancers Underlie Ovarian Cancer Susceptibility at the 8q24.21 Locus , Anxhela Gjyshi Gustafson

Quantitative Proteomics to Support Translational Cancer Research , Melissa Hoffman

A Systems Chemical Biology Approach for Dissecting Differential Molecular Mechanisms of Action of Clinical Kinase Inhibitors in Lung Cancer , Natalia Junqueira Sumi

Investigating the Roles of Fucosylation and Calcium Signaling in Melanoma Invasion , Tyler S. Keeley

Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage , Katrina E. Kelly

Investigation of Alcohol-Induced Changes in Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics , Crystina Leah Kriss

Off-Target Based Drug Repurposing Using Systems Pharmacology , Brent M. Kuenzi

Investigation of Anemarrhena asphodeloides and its Constituent Timosaponin-AIII as Novel, Naturally Derived Adjunctive Therapeutics for the Treatment of Advanced Pancreatic Cancer , Catherine B. MarElia

The Role of Phosphohistidine Phosphatase 1 in Ethanol-induced Liver Injury , Daniel Richard Martin

Theses/Dissertations from 2017 2017

Changing the Pathobiological Paradigm in Myelodysplastic Syndromes: The NLRP3 Inflammasome Drives the MDS Phenotype , Ashley Basiorka

Modeling of Dynamic Allostery in Proteins Enabled by Machine Learning , Mohsen Botlani-Esfahani

Uncovering Transcriptional Activators and Targets of HSF-1 in Caenorhabditis elegans , Jessica Brunquell

The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability. , Lillian Campos-Doerfler

Mechanisms of IKBKE Activation in Cancer , Sridevi Challa

Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens , Renee Fleeman

Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer , Jeremy S. Frieling

Disorder Levels of c-Myb Transactivation Domain Regulate its Binding Affinity to the KIX Domain of CREB Binding Protein , Anusha Poosapati

Role of Heat Shock Transcription Factor 1 in Ovarian Cancer Epithelial-Mesenchymal Transition and Drug Sensitivity , Chase David Powell

Cell Division Regulation in Staphylococcus aureus , Catherine M. Spanoudis

A Novel Approach to the Discovery of Natural Products From Actinobacteria , Rahmy Tawfik

Non-classical regulators in Staphylococcus aureus , Andy Weiss

Theses/Dissertations from 2016 2016

In Vitro and In Vivo Antioxidant Capacity of Synthetic and Natural Polyphenolic Compounds Identified from Strawberry and Fruit Juices , Marvin Abountiolas

Quantitative Proteomic Investigation of Disease Models of Type 2 Diabetes , Mark Gabriel Athanason

CMG Helicase Assembly and Activation: Regulation by c-Myc through Chromatin Decondensation and Novel Therapeutic Avenues for Cancer Treatment , Victoria Bryant

Computational Modeling of Allosteric Stimulation of Nipah Virus Host Binding Protein , Priyanka Dutta

Cell Cycle Arrest by TGFß1 is Dependent on the Inhibition of CMG Helicase Assembly and Activation , Brook Samuel Nepon-Sixt

Gene Expression Profiling and the Role of HSF1 in Ovarian Cancer in 3D Spheroid Models , Trillitye Paullin

VDR-RIPK1 Interaction and its Implications in Cell Death and Cancer Intervention , Waise Quarni

Regulation of nAChRs and Stemness by Nicotine and E-cigarettes in NSCLC , Courtney Schaal

Targeting Histone Deacetylases in Melanoma and T-cells to Improve Cancer Immunotherapy , Andressa Sodre De Castro Laino

Nonreplicative DNA Helicases Involved in Maintaining Genome Stability , Salahuddin Syed

Theses/Dissertations from 2015 2015

Functional Analysis of the Ovarian Cancer Susceptibility Locus at 9p22.2 Reveals a Transcription Regulatory Network Mediated by BNC2 in Ovarian Cells , Melissa Buckley

Exploring the Pathogenic and Drug Resistance Mechanisms of Staphylococcus aureus , Whittney Burda

Regulation and Targeting of the FANCD2 Activation in DNA Repair , Valentina Celeste Caceres

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UKnowledge > College of Medicine > Microbiology, Immunology, and Molecular Genetics > Theses & Dissertations

Theses and Dissertations--Microbiology, Immunology, and Molecular Genetics

Theses/dissertations from 2024 2024.

AZITHROMYCIN ALCHEMY: A JOURNEY FROM PRECISION IMMUNOMODULATION TO TARGET EXPLORATION AND BEYOND , Hodaossadat Saghaeiannejad Esfahani

THE ROLE OF INTRACELLULAR GROWTH DURING THE SYSTEMIC SPREAD OF LISTERIA MONOCYTOGENES , Jamila S. Tucker

Theses/Dissertations from 2023 2023

Investigation of Key Mechanisms of Contact Dependent Growth Inhibition Systems in Burkholderia cepacia Complex Species , Zaria K. Elery

Investigating the relationship between metabolic reprogramming and peripheral CD4+ T-cell inflammation in human type 2 diabetes pathogenesis , Gabriella Kalantar

SUBSTRATE SELECTION AND EFFECTOR GATING IN THE HELICOBACTER PYLORI CAG TYPE IV SECRETION SYSTEM , Mackenzie E. Ryan

Theses/Dissertations from 2021 2021

APPLICATION OF GENETIC TECHNIQUES TO INVESTIGATE CHLAMYDIA TRACHOMATIS TYPE III SECRETION EFFECTOR BIOLOGY , Gabrielle Keb

CHARACTERIZING THE PHYSIOLOGY AND GENETICS OF CONTACT DEPENDENT GROWTH INHIBITON SYSTEMS IN BURKHOLDERIA SPECIES , Alice Elizabeth Oates

Theses/Dissertations from 2020 2020

Elucidating the Complex Signaling Events Driving Intestinal Stem Cell Plasticity Following Injury , Evan Lynch

MAST CELLS AS NOVEL EFFECTOR CELLS IN THE PATHOGENESIS OF CHRONIC GRAFT-VERSUS-HOST DISEASE , Ethan Strattan

Theses/Dissertations from 2019 2019

THE ROLE OF CD8 T CELL IMMUNODOMINANCE AND REGULATORY T CELLS IN NEONATAL IMMUNITY TO INFLUENZA VIRUS , Luke Heil

EVOLUTION OF THE ZHX TRANSCRIPTION FACTOR FAMILY AND ANALYSIS OF ZHX2 TARGET GENES CYP2A4 AND CYP2A5 IN MOUSE LIVER , Alexandra Nichole Nail

FUNCTIONAL ANALYSES OF THE DNA- AND RNA-BINDING PROTEIN SPOVG IN BORRELIA BURGDORFERI , Christina R. Savage

Theses/Dissertations from 2018 2018

INSIGHTS INTO KEY GENE REGULATORY NETWORKS IN BORRELIA BURGDORFERI , William Kenneth Arnold

THE ROLE OF PRO-INFLAMMATORY MEDIATORS IFNβ AND PROSTAGLANDIN E2 IN SUPPRESSION OF INNATE IMMUNITY TO LISTERIA MONOCYTOGENES , Michelle G. Pitts

Theses/Dissertations from 2017 2017

SUPPRESSION OF ANTI-TUMOR IMMUNITY IN CHRONIC LYMPHOCYTIC LEUKEMIA VIA INTERLEUKIN-10 PRODUCTION , Sara Alhakeem

ANTISENSE AFP TRANSCRIPTS IN MOUSE LIVER AND THEIR POTENTIAL ROLE IN AFP GENE REGULATION , Maria S. Dixon

IMMUNE EVASION BY DIVISION OF LABOR: THE TROPHIC LIFE CYCLE STAGE OF PNEUMOCYSTIS MURINA SUPPRESSES INNATE IMMUNITY TO THIS OPPORTUNISTIC, FUNGAL PATHOGEN , Heather M. Evans

ROLE OF INTRACELLULAR GROWTH DURING THE GASTROINTESTINAL STAGE OF LISTERIA MONOCYTOGENES INFECTION , Grant Steven Jones

NOVEL ROLE OF PROSTATE APOPTOSIS RESPONSE-4 TUMOR SUPPRESSOR IN B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA , Mary Kathryn McKenna

THERAPEUTIC POTENTIAL OF TARGETING REACTIVE OXYGEN SPECIES (ROS) STRESS IN MYELODYSPLASTIC SYNDROME (MDS) , Karine Z. Oben

Theses/Dissertations from 2016 2016

Expression of Zinc Fingers and Homeoboxes 2 (Zhx2) and Zhx2 Target Genes in Multiple Tissues of Wild-Type and Zhx2 Knockout Mice , Minen Al-Kafajy

Theses/Dissertations from 2015 2015

THE ROLE OF BATF2 IN LPS/IFNγ POLARIZED MACROPHAGES , Marie A. Gehman

Theses/Dissertations from 2013 2013

ON T CELL FATE DECISIONS: RETINOL, METABOLISM AND ITREG DIFFERENTIATION , Gavin I. Ellis

Theses/Dissertations from 2012 2012

Role of the Immune System and Bioactive Lipids in Trafficking Bone Marrow-Derived Stem Cells in Patients with Ischemic Heart Disease , Ahmed Abdel-Latif

INSIGHTS INTO HEPATIC ALPHA-FETOPROTEIN GENE REGULATION DURING LIVER DEVELOPMENT AND DISEASE , Erica Leigh Clinkenbeard

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Home > FACULTIES > Microbiology & Immunology > MNI-ETD

Microbiology & Immunology Theses and Dissertations

This collection contains theses and dissertations from the Department of Microbiology & Immunology, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository

Theses/Dissertations from 2024 2024

Investigating the effects of physical maturation and sexual debut on HIV-1 susceptibility in adolescent males in Rakai, Uganda , Omar Almomani

Characterizing and Applying a Nasal Organotypic Model to Investigate the Effects of Immune Profile Types on SARS-CoV-2 Susceptibility , Victor H.K. Lam

Effect of sodium thiosulfate pre-treatment on renal ischemia-reperfusion injury , Pierce BR Nelson

Role of Ikzf3 as a Driver Mutation in B Cell Acute Lymphoblastic Leukemia , Heidi Rysan

Contribution of Streptolysin O and Streptolysin S to Streptococcus pyogenes Infections in HLA-Transgenic Mice , Blake A. Shannon

Regulation of ZAP-70 post-translational modifications by HIV-1 accessory proteins Nef and Vpu , Jack E. Teplitsky

Role of ETV5 Mutations in B Cell Acute Lymphoblastic Leukemia , Joshua S. Yi

Investigating the role of two-component regulatory systems in regulating FnBP-A of Staphylococcus aureus , Yunqi Zhang

Theses/Dissertations from 2023 2023

The Effect of Kidney Preservation at 10°C with Hemopure and Hydrogen Sulfide Donor, Sodium Thiosulfate, in a Syngeneic Model of Rat Renal Transplantation , Maria Abou Taka

Mechanisms of lactic acid bacteria secretions as anti-Helicobacter pylori agents , Daelyn Carroll

Investigating the clinical and microbial factors contributing to calcium-containing kidney stone disease , John A. Chmiel

Elucidating the Biomechanics of MERTK-Mediated Efferocytosis , Brandon Hayato Dickson

SARS-CoV-2 infectivity potential in municipal wastewater: Implications for public health & water treatment , Justin Donovan

Development of a high-throughput approach for testing optimal fecal microbiota transplant material , Shaeley Jae Gibbons

The Role of Mucosa-Associated Invariant T Cells in an Autochthonous Mouse Model of Bladder Cancer , Inbar A. Habaz

Evaluating the role of GraS and FadXDEBA in promoting Staphylococcus aureus adaptation to host-derived fatty acids encountered at sites of colonization and infection , Robert C. Kuiack

The Effects of Cell Envelope Localization of FnBP-A on Staphylococcus aureus FnBP-A Dependent Phenotypes , Camille LeBlanc

The Role of the MEK1/2-ERK-RSK Signalling Axis in Innate Immune Memory , Rachel Low

Identification of a PU.1-regulated repressive region in Aicda gene locus , Allanna MacKenzie

Evolution of overlapping reading frames in virus genomes , Laura Muñoz Baena

Molecular Characterization of the Antiviral Properties of the Small HERC Family of Proteins , Ermela Paparisto

Effect of pharmacological inhibition of endogenous hydrogen sulfide production on bladder cancer progression , Sydney Relouw

Exploration of the Immune Landscape of EBV-associated Gastric Cancers , Mikhail Salnikov

Novel Roles of PACS-1 Within the Nucleus and the Regulated Secretory Pathway , Steven Trothen

Characterization of T-Cell Responses to Homocitrulline in a Mouse Model of Rheumatoid Arthritis , Sofya Ulanova

Inflammation in the Neovaginal Microenvironment of Transfeminine Individuals , Hannah M.J. Wilcox

Theses/Dissertations from 2022 2022

Investigation of the Binding and Outside-In Signalling Mechanisms of Anti-CD11d Acute Neurotrauma Therapy , Eoin N. Blythe

TetR family regulator FarR variation controls antimicrobial fatty acid efflux in Staphylococcus aureus , Camryn M. Bonn

The Role of Coagulase-Negative Staphylococcal Secreted Products on Staphylococcus aureus and Staphylococcus lugdunensis Infections , Denny Chin

Characterizing the Function of B Cells that Accumulate in the Inflamed Central Nervous System in Anti-Myelin Autoimmunity , Lika Chowdhury

The Streptococcus pyogenes hyaluronic acid capsule prevents neutrophil clearance, and greater insights into the streptococcal M protein as a vaccine candidate and driver of heart dysfunction , Jacklyn Hurst

In Vitro and In Vivo Characterization of the Metallodrug BOLD-100 as an Inhibitor of SARS-CoV-2 Replication , Daniel S. Labach

Regulation of MHC II Trafficking and Expression by Host and Viral Factors , Alex Lac

Design and Synthesis of Nef:SFK Interaction Inhibitors for Application in an Immune-directed HIV-1 Cure , Antony Lurie

Immunophenotyping and Functional Assessment of Antiviral CD8+ T Cells in a CLP Mouse Model of Immunosuppression , Alex R. Michaud

Herbicide Mediated Selection of Sulfonamide Resistant E. coli , Laura P. Muntz

Campylobacter jejuni Capsular Heptose: Moderation of Host Macrophages and Substrate Channeling During Synthesis , Matthew Myles

The role of reactive oxygen species in the accumulation of driver mutations in B cell acute lymphoblastic leukemia , Mia P. Sams

The Effect of Oral and Topical Antibiotics on Foreskin Inflammation and HIV Target Cells in Ugandan Men. , Zhongtian (Eric) Shao

Screening for purine transporters in S. aureus , Tothong Sonpaveerawong

The Expanding Roles of PACS-1 and PACS-2 in Cellular Physiology: Beyond Vesicular Protein Trafficking , Rong Xuan Zang

Theses/Dissertations from 2021 2021

Mucosa-Associated Invariant T Cells Undergo Phenotypic Changes Following Fecal Microbiota Transplantation , Jenna M. Benoit

Microbial innovations for disease management in honey bees , Brendan A. Daisley

Investigating the in vivo mechanism behind fibronectin binding protein-mediated hypervirulence of Staphylococcus aureus , Jaclyn A. Diamond

21°C is the emerging ideal temperature for kidney preservation in the presence of hydrogen sulfide , Smriti Juriasingani

Fishing for the right probiotic: Investigating the mechanism of mucosal-bacterial interactions at the interface of health and productivity in salmonid aquaculture , Luana Langlois

Testing a Novel Peptide-Infused Cream for Treatment of Rheumatoid Arthritis in DR4tg Mice , Alisha J. Moynahan

HIV-1 Drug Resistance to Integrase Strand Transfer Inhibitors in HIV-1 non-B Subtypes , Emmanuel Ndashimye

Metabolic Reprogramming By DNA Tumour Viruses , Martin Prusinkiewicz

Metabolic origins of urogenital malodour in women and their relationship with their microbiota: can probiotics help? , Scarlett Puebla Barragan

The E26 Transformation-Specific-Family Transcription Factor Spi-C is Dynamically Regulated by External Signals in B Cells , Hannah L. Raczkowski

Generation and Characterization of an In Vitro Organotypic Foreskin Model for Future Study of the Penile Microbiome , Geoffrey J. Rempel

The impacts of psychological stress on innate-like invariant T cell survival, phenotype, and function , Patrick Rudak

A Workflow to Analyze ETHcD Mass Spectrometry Data for Studying HIV gp120 Glycosylation , Yingxue Sun

Meningeal B cells in central nervous system autoimmunity: Their phenotype and susceptibility to therapeutic depletion , Yodit Tesfagiorgis

Characterization and Discovery of Short Linear Motifs Mediating Protein Nuclear Import , Tanner M. Tessier

The Ability of Lactobacillus spp. to Limit Extracellular ATP Release by Urogenital Bacteria , Hannah Wilcox

Differential Effects of KIM-1 in Subcutaneous and Orthotopic Renca Models of Kidney Cancer , Demitra M. Yotis DY

Protective benefits of sodium thiosulfate-supplemented UW solution against prolonged cold ischemia-reperfusion injury during renal transplantation. , Max Y. Zhang Mr.

Theses/Dissertations from 2020 2020

Characterizing the Role of the Microbiome in Kidney Stone Disease , Kaitlin F. Al

Targeting CD5 to enhance immune T cell activation and function in treatment of solid tumours , Faizah Alotaibi

HPV Mediated Antagonism of the IL-18 Proinflammatory Pathway in Head and Neck Cancer , Wyatt W. Anderson

Investigation of the growth and survival of Staphylococcus aureus in CFTR-deficient macrophages , Bita Azad

Staphylococcus aureus small colony variants use heme and staphyloferrin B for iron acquisition , Izabela Z. Batko

Understanding Neonicotinoid Related Immunosuppression: A Potential for Beneficial Bacterial Intervention , John A. Chmiel

Exploiting the immunomodulatory potentials of iNKT cells in sepsis and cancer. , Joshua Choi

Optimizing Fecal Microbiota Transplantations For Therapeutic Use Beyond Clostridioides difficile Infection , Laura J. Craven

Cell-free DNA Release During Programmed Cell Death in Kidney Ischemia Reperfusion Injury , Alexander Dionne

The development of bacterial magnetic resonance imaging for microbiota analyses , Sarah C. Donnelly

Inducing DNA-Mismatch Repair Deficiency In Tumours: A Strategy To Enhance Anti-Tumour Immunity , Mikal El-Hajjar

Investigating the Regulation of Fatty Acid Efflux Pump FarE by TetR Family Regulator FarR in Staphylococcus aureus , Katherine A. Ferguson

Elucidating the Role of Host Tim-1 in Anti-tumour Immunity , Ingrid Hon

Kidney Injury Molecule-1 Mediated Phagocytosis and Its Therapeutic Application in Ameliorating Renal Transplant Ischemia Reperfusion Injury , Ji Yun Lee

B Cell Acute Lymphoblastic Leukemia is Driven by Activating Janus Kinase Mutations Cooperating with Spi1 and Spib Deletions in a Murine Model , Michelle Lim

Development and evaluation of a heterogenous virus-like particle (VLP) formulation to achieve HIV-1 latency reversal and cure. , Joshua P. Pankrac

Designing a Novel HIV-1 Candidate Vaccine , Rahul Pawa

Identification of the Signalosome and Signaling Pathway of the Efferocytic Receptor MERTK , Tarannum Tasnim

Theses/Dissertations from 2019 2019

Potential role of extracellular ATP released by bacteria in bladder infection and contractility , Behnam Abbasian

Brain-specific and systemic inflammatory response following repetitive concussive impact in a mouse model , So Young Eo

The Group A Streptococci Bacteriocins Facilitate a Competitive Advantage During Nasopharyngeal Infection , Lana Estafanos

The Epigenetic And Immune Landscapes Of HPV+ Tumor Microenvironments , Steven F. Gameiro

Utilizing FIV (Feline Immunodeficiency Virus) to develop a novel animal model to study HIV (Human Immunodeficiency Virus) , Ankita Suryakant Kambli

Designing An Optimal HIV-1 Env Immunogen For The Vesicular Stomatitis Virus Vaccine Platform And Elucidating The Role Of HIV-1 Nef In Env Trafficking , Jason Knapp

Novel insights into the genomic integration site landscape of HIV-1 and other retrovirus genera , Hinissan P. Kohio

The role of kidney injury molecule-1 in the metastasis of renal cell carcinoma , Jasper Lee

Encountering Lectins In The Recipient Mucosa: Implications Of N-linked Glycosylation On HIV-1 Transmission , Adam Meadows

Endogenous, controlled expression of anti-HIV-1 broadly neutralizing antibody , Darshit Patel

Role of the fibronectin-binding, collagen-binding, T-antigen region during nasopharyngeal infection by Streptococcus pyogenes , Akshay Sule

HIV-1 Group M Subtype Fitness, Disease Progression, and Entry Efficiency , Colin M. Venner

Mucosa-Associated Invariant T Cell Roles And Local Responses In Cell-Mediated Immunity To Influenza A Virus , Christine Marie Wardell

Metabolomic and Genomic Analysis of Lactobacillus crispatus Vaginal Isolates , Emiley Watson

Virally Packaged RNA in Virus-Like Particle Vaccines Enhances Antigenicity and Augments Latency Reversal of HIV-1 , Chanuka Wijewardhana

Determining the Relative Transmission Fitness of HIV-1 Subtypes A, B, C, and D , Spencer Yeung

The Role of Defective Macrophage Efferocytosis During Early Atherosclerosis in Humans , Charles Yin

Theses/Dissertations from 2018 2018

Characterization of Urinary Microbiome and Their Association with Health and Disease , Yige Bao

Characterization of interleukin (IL)-1β regulatory elements and chromatin conformation in macrophage activation , Woohyun Cho

Determining the Molecular Mechanisms of PACS-1-mediated Protein Sorting , Brennan S. Dirk

19F-MRI to Monitor Therapeutic Cell Migration and Distribution , Corby Fink

Inhibition of NK cell-mediated Cytotoxicity by Tubular Epithelial Cell Expression of Clr Proteins , Benjamin B. Fuhrmann

Interferon-induced HERC5 is a novel and potent inhibitor of Ebola virus-like particle production , Nina Hunt

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Microbiology and Immunology

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View all UBC microbioloby and immunology theses via UBC Open Collections. Here are some of the most recent ones.

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Ph.D. in Microbiology

The program leading to the Ph.D. degree is designed to develop the student’s ability to pursue independent and original research in microbiology and allied fields, communicate the results of such research to the scientific community and serve as an effective teacher. Students normally enter the doctoral program after receiving a master’s degree. Four years are required to complete the program.

Ph.D. Student learning outcomes

Program purpose.

The Ph.D. program in the School of Life Sciences at the University of Hawaii is designed to give students the academic and technical skills to become independent scientists and researchers. We strive to provide each graduate student with broad knowledge in microbiology and in-depth knowledge in their area of specialization. Students are trained in both traditional and state-of-the-art technologies to be applied to the design and conduct of original research projects. Additionally, students have access to both basic and advanced coursework to further their academic and research goals.

Student Learning Outcomes

• Design microbiological or immunological experiments at an advanced graduate level.
• Demonstrate proficiency with a variety of classical and modern microbiology techniques.
• Read, understand and evaluate current literature in their discipline. Produce significant scientific research results.
• Research results and interpretations of those results should be clearly presented both orally and in peer reviewed publications.
• Develop awareness and perspective as a member of a local, national and global scientific community.
• Compete successfully for productive employment or postdoctoral training in industry or academic institutions.
• General Information and Procedures for the Ph.D. Degree

Advancement to Candidacy (Ph.D)

Advancement to doctoral candidacy involves four steps:, 1. comprehensive written exam..

The comprehensive exam consists of two sections.

• A general knowledge section that tests students in all areas of microbiology and contains questions that all professional microbiologists should be capable of answering.
• A current topics section that tests students on two current topics in microbiology.

This section of the exam tests a student’s ability to independently research and understand a concept, pathway, phenomenon, or other aspect of microbiology that is emerging at the forefront of the field. Students will be given the two topics a minimum of six weeks prior to the exam date.

Sections of the exam will be administered on consecutive days once each semester and summer term. This is a closed-book exam. The student will have 3 hours to complete each section. Exams will be written and graded by a three-member panel of Microbiology faculty. Graded exams will be returned to students within one week of their completion.

The written comprehensive may be repeated the following semester if a non-passing grade is received after the first attempt. Two successive non-passing grades will result in removal from the Ph D program.

2. Comprehensive oral exam.

A comprehensive oral exam will be administered by the three Microbiology faculty approximately one week after receipt of the graded written exam. Questions on the oral exam will focus on, but are not limited to, responses to questions on the written exam. A student’s mentor cannot serve on the comprehensive exam panel.

It is strongly recommended that students take the comprehensive exam in their fifth semester or earlier (third semester or earlier for students with a UH Microbiology MS degree). The first attempt at the comprehensive exam must be completed by the end of the sixth semester of study.

3. Dissertation written proposal.

Upon successfully completing the comprehensive exam, a written document describing the research that will constitute the student’s doctoral dissertation will be submitted to members of the student’s doctoral committee.

4. Dissertation oral proposal.

A succinct presentation of the proposal will be made to the student’s doctoral committee approximately 2 – 4 weeks after distribution of the written proposal. Committee members will be permitted to question the student on the research proposal. At the end of the proposal meeting, committee members will determine if the proposal is acceptable and whether the student is ready to advance to candidacy. Upon acceptance of the proposal, the student is conferred “doctoral candidate” status.

It is strongly recommended that students complete the oral dissertation proposal by the end of their sixth semester of the program.

Course Requirements

Completion of 30 credit hours as follows:

• 12 cr. of classes 600 level and up, excluding MICR 699. It is expected that the majority of these classes will be in Microbiology. Classes from outside the program may be included, upon approval of student’s committee chair. Up to 3 credits of MICR695 may be applied toward the degree.
• 7 cr. of Directed Research, MICR 699.
• 1 cr. Seminar, MICR 690.
• 1 cr. Thesis, MICR 800.
• (e) 9 cr. of classes, which can include 400 level and graduate-level Microbiology classes. Directed Research (MICR 699) may not be included. Graduate-level classes from outside the program may be included, upon approval of student’s committee chair.

Note: certain adjustments can be considered for those with a M.S. degree in Microbiology or closely related field.

Teaching Requirement

At least one year of teaching experience is considered part of the training of the Ph.D. candidate and is a requirement for the degree. This requirement can be waived for equivalent experience or for other extraordinary circumstances.

Seminar Requirement

The student is expected to give at least one departmental seminar (MICR 690) in addition to the defense seminar at the end of the student’s program.

Ph.D. Language Examination

There is no program foreign language requirement.

Dissertation Review

Much of the Dissertation writing and review is done under the supervision of the major professor (mentor). Thus, a sufficient period must be allowed for first and second draft revisions. This period is not dictated in any way by the University or Program and will depend on the scientific and editorial qualities of the drafts. Also, it is not unlikely that a mentor will have several theses or dissertations to review in a semester. If the dissertation has not been properly reviewed and drafted by the student and his/her mentor, the other committee members are not obligated to read or judge the document until it is in reasonable shape.

Dissertation Defense

This will be given as an advertised public seminar of approximately one hour duration with an unlimited questioning period to follow. Consult the Graduate Division for advertising deadlines.

Dissertation Copies

In addition to the requirements of the Graduate Division, students are required to provide two bound copies of their dissertation to the Program before graduation, one of which goes to the chairman of the dissertation committee.

Remember:   It is the personal responsibility of each student to see that all requirements are fulfilled and all deadlines met in a timely manner. See the university general catalog for the official calendars.

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Olympic Breakdancer Raygun Has PhD in Breakdancing?

Rachael gunn earned a zero in breakdancing at the paris 2024 olympic games., aleksandra wrona, published aug. 13, 2024.

About this rating

Gunn's Ph.D. thesis, titled "Deterritorializing Gender in Sydney's Breakdancing Scene: a B-girl's Experience of B-boying," did cover the topic of breakdancing. However ...

... Gunn earned her Ph.D. in cultural studies. Moreover, a "PhD in breakdancing" does not exist as an academic discipline.

On Aug. 10, 2024, a rumor spread on social media that Rachael Gunn (also known as "Raygun"), an Australian breakdancer who competed in the 2024 Paris Olympics, had a Ph.D. in breakdancing. "This australian breakdancer has a PhD in breakdancing and dance culture and was a ballroom dancer before taking up breaking. I don't even know what to say," one X post on the topic read .

"Australian Olympic breakdancer Rachael Gunn has a PhD in breakdancing and dance culture," one X user wrote , while another asked, "Who did we send? Raygun, a 36-year-old full-time lecturer at Sydney's Macquarie University, completed a PhD in breaking culture and is a lecturer in media, creative arts, literature and language," another X user wrote .

The claim also spread on other social media platforms, such as Reddit and Instagram . 

"Is she the best break dancer? No. But I have so much respect for going on an international stage to do something you love even if you're not very skilled at it," one Instagram user commented , adding that, "And, I'm pretty sure she's using this as a research endeavor and will be writing about all our reactions to her performance. Can't wait to read it!"

In short, Gunn's Ph.D. thesis, titled "Deterritorializing Gender in Sydney's Breakdancing Scene: A B-girl's Experience of B-boying," indeed focused on the topic of breakdancing. However, Gunn earned her Ph.D. in cultural studies, not in breakdancing. Furthermore, it's important to note that a "PhD in breakdancing" does not exist as an academic discipline. 

Since Gunn's research focused on the breakdancing community, but her degree is actually in the broader field of cultural studies, we have rated this claim as a "Mixture" of truths.

Gunn "secured Australia's first ever Olympic spot in the B-Girl competition at Paris 2024 by winning the QMS Oceania Championships in Sydney, NSW, Australia," the Olympics official website informed . 

Gunn earned a zero in breakdancing at the Paris 2024 Olympic Games and clips of her routine went viral on social media, with numerous users creating memes or mocking dancer's moves. "As well as criticising her attire, social media users mocked the Australian's routine as she bounced around on stage like a kangaroo and stood on her head at times," BBC article on the topic read . 

The website of the Macquarie University informed Gunn "is an interdisciplinary and practice-based researcher interested in the cultural politics of breaking" and holds a Ph.D. in cultural studies, as well as a bachelor of arts degree (Hons) in contemporary music: 

Rachael Gunn is an interdisciplinary and practice-based researcher interested in the cultural politics of breaking. She holds a PhD in Cultural Studies (2017) and a BA (Hons) in Contemporary Music (2009) from Macquarie University. Her work draws on cultural theory, dance studies, popular music studies, media, and ethnography. Rachael is a practising breaker and goes by the name of 'Raygun'. She was the Australian Breaking Association top ranked bgirl in 2020 and 2021, and represented Australia at the World Breaking Championships in Paris in 2021, in Seoul in 2022, and in Leuven (Belgium) in 2023. She won the Oceania Breaking Championships in 2023.

Gunn's biography further revealed that she is a member of the Macquarie University Performance and Expertise Reasearch Centre, and has a range of teaching experience at undergraduate and postgraduate levels "across the areas of media, creative industries, music, dance, cultural studies, and work-integrated learning." 

Moreover, it informed her research interests included, "Breaking, street dance, and hip-hop culture; youth cultures/scenes; constructions of the dancing body; politics of gender and gender performance; ethnography; the methodological dynamics between theory and practice."

Gunn earned her Ph.D. from the Department of Media, Music, Communications, and Cultural Studies within the Faculty of Arts at Macquarie University. Below, you can find the abstract of her paper, shared by the official website of Macquarie University:

This thesis critically interrogates how masculinist practices of breakdancing offers a site for the transgression of gendered norms. Drawing on my own experiences as a female within the male-dominated breakdancing scene in Sydney, first as a spectator, then as an active crew member, this thesis questions why so few female participants engage in this creative space, and how breakdancing might be the space to displace and deterritorialise gender. I use analytic autoetthnography and interviews with scene members in collaboration with theoretical frameworks offered by Deleuze and Guttari, Butler, Bourdieu and other feminist and post-structuralist philosophers, to critically examine how the capacities of bodies are constituted and shaped in Sydney's breakdancing scene, and to also locate the potentiality for moments of transgression. In other words, I conceptualize the breaking body as not a 'body' constituted through regulations and assumptions, but as an assemblage open to new rhizomatic connections. Breaking is a space that embraces difference, whereby the rituals of the dance not only augment its capacity to deterritorialize the body, but also facilitate new possibilities for performativities beyond the confines of dominant modes of thought and normative gender construction. Consequently, this thesis attempts to contribute to what I perceive as a significant gap in scholarship on hip-hop, breakdancing, and autoethnographic explorations of Deleuze-Guattarian theory.

In a response to online criticism of her Olympics performance, Gunn wrote on her Instagram profile: "Don't be afraid to be different, go out there and represent yourself, you never know where that's gonna take you":

We have recently investigated other 2024 Paris Olympics' -related rumors, such as:

• Lifeguards Are Present at Olympic Swimming Competitions?
• Hobby Lobby Pulled $50M in Ads from 2024 Paris Olympics?
• 2024 Paris Olympics Are 'Lowest-Rated' Games in Modern History?

Gunn, Rachael Louise. Deterritorializing Gender in Sydney's Breakdancing Scene: A B-Girl's Experience of B-Boying. 2022. Macquarie University, thesis. figshare.mq.edu.au, https://doi.org/10.25949/19433291.v1.

---. Deterritorializing Gender in Sydney's Breakdancing Scene: A B-Girl's Experience of B-Boying. 2022. Macquarie University, thesis. figshare.mq.edu.au, https://doi.org/10.25949/19433291.v1.

Ibrahim, Nur. "Lifeguards Are Present at Olympic Swimming Competitions?" Snopes, 8 Aug. 2024, https://www.snopes.com//fact-check/lifeguards-paris-olympics-swimming/.

"Olympic Breaking: Criticism of Viral Breakdancer Rachael Gunn - Raygun - Condemned by Australia Team." BBC Sport, 10 Aug. 2024, https://www.bbc.com/sport/olympics/articles/c2dgxp5n3rlo.

ORCID. https://orcid.org/0000-0002-1069-4021. Accessed 12 Aug. 2024.

Paris 2024. https://olympics.com/en/paris-2024/athlete/-raygun_1940107. Accessed 12 Aug. 2024.

Saunders, Grant Leigh, and Rachael Gunn. "Australia." Global Hip Hop Studies, vol. 3, no. 1–2, Dec. 2023, pp. 23–32. Macquarie University, https://doi.org/10.1386/ghhs_00060_1.

Wazer, Caroline. "2024 Paris Olympics Are 'Lowest-Rated' Games in Modern History?" Snopes, 1 Aug. 2024, https://www.snopes.com//fact-check/paris-olympics-lowest-rated-games/.

---. "Hobby Lobby Pulled $50M in Ads from 2024 Paris Olympics?" Snopes, 8 Aug. 2024, https://www.snopes.com//fact-check/olympics-hobby-lobby-ads/.

By Aleksandra Wrona

Aleksandra Wrona is a reporting fellow for Snopes, based in the Warsaw, Poland, area.

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Clinical Implications of New Drinking Water Regulation for ‘Forever Chemicals’ – JAMA

Read article - Rachel Criswell, an adjunct professor of epidemiology, writes an opinion piece about the impact of new safe drinking water regulations for PFAS. "The new EPA regulation, far below the previous drinking water health advisory of 70 parts per trillion, and recent media interest will lead many patients to question whether they have been exposed to unsafe PFAS levels," Criswell writes.

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