journal of nano research

Journal of Nano Research

• Journal Search
• Journal Details

Note: The following journal information is for reference only. Please check the journal website for updated information prior to submission.

J NANO RES-SW

MATERIALS SCIENCE, MULTIDISCIPLINARY

NANOSCIENCE & NANOTECHNOLOGY

PHYSICS, APPLIED

Category	Quartile	Rank
Physics and Astronomy - General Physics and Astronomy	Q2	#96/240
Physics and Astronomy - General Materials Science	Q3	#241/453

Science Citation Index Expanded (SCIE)	Social Sciences Citation Index (SSCI)
Indexed	-

Category (Journal Citation Reports 2023)	Quartile
MATERIALS SCIENCE, MULTIDISCIPLINARY - SCIE	Q4
NANOSCIENCE & NANOTECHNOLOGY - SCIE	Q4
PHYSICS, APPLIED - SCIE	Q3

• Popular journals in the same field
• Recent articles

Verified Reviews

Find funding. review successful grants..

Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.

Add your recorded webinar

Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.

Journal of Nano Research Latest Publications

Total documents, published by trans tech publications.

• Latest Documents
• Most Cited Documents
• Contributed Authors
• Related Sources
• Related Keywords

Effects of the Molecular Weight of PCz on Selective Extraction of Large-Diameter Semiconducting Single-Walled Carbon Nanotubes

Due to the difficulty in the selective synthesis of semiconductor (s-) and metal (m-) single-walled carbon nanotubes (SWCNTs), we still need to explore the selective extraction technology of s-SWCNTs. Using Poly[9-(1-octylonoyl)-9H-carbazole-2,7-diyl] (PCz) extraction of s-SWCNTs has attracted extensive attention in recent years, because it can selective extraction of large-diameter s-SWCNTs with high purity. However, influence of the molecular weight of this polymer on the s-SWCNTs selective extraction properties remains unclear. In this study, we used PCz with different average molecular weights to study the ability of selective extraction s-SWCNTs from pristine arc discharge carbon nanotubes. Spectra studies indicate that compared to the PCz with lower molecular weight, the PCz with higher molecular weight has better selective extraction ability, and can help to obtain s-SWCNTs with higher purity (>99%) and high yield. FETs devices have been prepared by s-SWCNTs obtained via PCz with higher molecular weight exhibit higher on/off ratio, lower off current and lower subthreshold swing. This work offers a reference of the design and synthesis of PCz polymer that performs sufficient selective ability in extracting s-SWCNTs with promising applications.

Effect of Single Walled Carbon Nanotubes on the Series Resistance and Trap Energy of Malachite Green Dye Based Organic Device

In this paper, we have estimated the series resistance (Rs) and the trap energy (Ec) of the sandwiched type Malachite Green (MG) dye-based organic device and have also observed the influence of single-walled carbon nanotubes (SWCNT) on both of these parameters. To form the organic device, we have used Indium Tin Oxide (ITO) coated glass as the front electrode and Aluminium (Al) as a back electrode by using the spin coating technique. The values of series resistance are measured from both I-V characteristics and by utilizing Cheung Function due to the non ideal behavior of organic devices. We have also extracted the values of Rs by using H (I) versus I plot and verified the values with the measured values of Rs from the Cheung function. The extracted values of series resistance using these three processes remain consistent with each other in showing that the values of series resistance have been reduced considerably in the presence of SWCNT. The trap energy has been estimated from the steady-state current-voltage characteristics. There is a significant correlation in between series resistance and the trap energy of the organic device. The presence of Single-Walled Carbon Nanotubes reduces the trap energy from 0.086 eV to 0.057 eV. Lowering of the trap energy of the metal-organic layer interface in presence of Single Walled Carbon Nanotubes attributes to the reduction of the value of the series resistance. The extracted value of Rs decreases from 0.154 MΩ to 0.0389 MΩ in presence of SWCNT. Decrease in the value of both of these parameters in the presence of SWCNT will definitely improve the charge transport mechanism of the organic device and thereby the conductivity.

Stability, Structural and Electronic Properties of Indium Phosphide Wurtzite-Diamantane Molecules and Nanocrystals: A Density Functional Theory Study

The density functional theory is applied for examining the electronic structure and spectroscopic properties for InP wurtzite molecules and nanocrystals. In this paper we present calculations of the energy gap, bond lengths, IR and Raman spectrum, reduced mass and force constant. The results of the presented work showing that the InP’s energy gap was fluctuated about to experimental bulk energy gap (1.49 eV). Results of spectroscopic properties including IR and Raman spectrum, reduced mass and force constant as a function of frequency were in accordance with the provided experimental results. In addition, the study of the Gibbs free energy proved the stability phase of InP wurtzoids against transition to InP diamondoids structure.

Study on the Tribological Mechanism of Ultrafine SiO2/MoS2 Powders in Complex Calcium Sulfonate Grease

The purpose of this work was to study and further clarify the anti-wear and anti-friction mechanism of ultrafine SiO2/MoS2 powders in the complex calcium sulfonate grease. In this paper, 15nm nanoSiO2, 1μm MoS2 and commercial NLGI Grade No.2 complex calcium sulfonate grease were used as the research objects, SEM, EDS and XPS were used to study the morphology, composition and film chemical constitution of the long friction wear spots of grease containing single nanoSiO2 powder, ultrafine MoS2 powder and the two compound powders, which formed in the process of four ball long friction. The results show that nanoSiO the grease plays a role in filling the undercut, ball bearings and polishing and forming high hardness Ca3Fe2(SiO4)3 and part of Fe2O3 anti-wear films in the process of long friction. The ultrafine MoS2 powder has a self-repairing effect to fill the grooves,forming the MoS2, MoO3 anti-friction films and Fe2(SO4)3 anti-wear film. The two powders in the composite grease have a synergistic effect, acting on the friction pair together, and simultaneously forming self-repairing anti-friction and anti-wear films, thereby further improving the tribological performance of the base grease.

The Role of Particles and Clusters Size on the Catalytic Activity of Different Types of Gold Nanocatalysts for Benzyl Alcohol Oxidation

: In this paper, activation procedures under size effects of some gold nanoparticles (Au101, Aunaked and Aucitrate) and nanoclusters (Au8 and Au9) immobilized on powder Norit® activated carbon (abbreviated to AC) and/or Vulcan carbon (abbreviated to VC) on the catalytic activity of gold nanocatalysts were studied. The gold nanostructures were activated through the washing procedure with a base in MilliQ water or hot toluene and then followed by heating in static air (abbreviated to W+S) or under vacuum (abbreviated to W+V) at 100 °C for 3 h. The highest activity of gold nanocatalysts for benzyl alcohol oxidation was obtained for activated (W+V) ‘naked’ gold nanoparticles immobilized on Norit® activated carbon when the gold nanoparticle diameters was ~4.4 nm.

Water Disinfection Using Silver and Zinc Oxide Nanoparticles

Waterborne disease has changed a basic challenge in human population. recently, the use of nanotechnology and application of nanomaterials for the control of pathogens in water is widely increased in research. Common indicator for microbial quality of water are determine presence of total and fecal coliforms. The purpose of this study was to evaluate the effect of Silver (Ag) and zinc oxide (ZnO) nanoparticles (NPs) and combination of them in removing total and fecal coliform bacteria from contaminated water. In this experimental study a synthetic solution was made by adding effluent to distilled water. In each run, the nano silver (20-100 μg /L) and ZnO NPs (0.25-2 mg/L) were added to contaminated water. The samples were tested by 15-tube series method based on the instruction 9221-B of 21th edition of standard method book on water and wastewater experiments. Bacteria removal efficiency were examined in contact times (15, 30,60, 90 and 120) minutes. Our data indicate a decrease in the number of bacteria (MPN) in the presence of the nanoparticles. Results revealed that the removal percentage of coliform bacteria removal increased with increasing the contact time and concentrations of nanoparticles. Ag NPs at a concentration of 100 μg /L and ZnO NPs at a concentration of 2 mg/L showed the highest percentage of removal bacteria and the combination of ZnO and Ag NPs have been high synergistic behavior against coliform bacteria in contaminated water. therefore, using a combination of ZnO and Ag NPs can become a new and efficient method for the removal of indicator bacteria from contaminated water.

Study of the Structure, Microstructure and Temperature Dependent Thermal Conductivity Properties of SrTiO3: Via Y3+ Substitution

Yttrium (Y) modified strontium titanate (SrTiO3) powders with initial concentration of Y in the range of 0 to 15 mol% were produced through sol-gel technique. X-ray diffraction (XRD) studies show that all the prepared compounds have a perovskite cubic structure with the space group (Pm3m). The lattice constant, lattice strain and crystallite size of the as-prepared samples were estimated from the XRD pattern which reveals the incorporation of Y into SrTiO3 system, moreover to investigate the quality of the prepared SrYT ceramics powder, the scanning electron microscopy (SEM) was used to determined investigate the morphology, grain size and its distribution. The analysis of the thermal conductivity measurements performed on the obtained powders revealed the effect of the combination of temperature and Y content on the thermal conductivity value, Indeed, the minimum thermal conductivity was 4.12 W/(mK) obtained with 15%Y at 464 K.

Nonlinear Behavior of Single Walled Carbon Nanotube Reinforced Aluminium Alloy Beam

This paper aims to analyze the nonlinear vibration of clamped-clamped buckled beams made of Aluminium alloy (Al-alloy) reinforced with uniformly dispersed Single Walled Carbon Nanotube (SWNT). The mean field homogenization technique is used to predict the effective material properties of the beams. The equation of motion governing the nonlinear behavior is solved using an exact method. The effects of various parameters including axial load, vibration amplitude, SWNT volume fraction, SWNT aspect ratio and beam slenderness ratio on the nonlinear frequency and on the phase trajectory plots for pre- and post-buckling states are studied.

Effect of Different Precursors Solution of NiO on the Properties of ZnO/NiO Nanocomposites Thin Films Grown by Spray Pyrolysis

In this paper, the influence of the precursors of nickel oxide (NiO) on the properties of ZnO/NiO nanocomposites thin films, grown by spray pyrolysis method, has been investigated. The nickel sulfate, nickel chloride and nickel nitrate have been used as precursors of NiO, each precursor has been mixed with Zinc oxide (ZnO)’ precursor to elaborate ZnO/NiO nanocomposites thin films with the method mentioned above. The aim of this paper is to confirm the similitude of precursors in the nanocomposites. For this reason, and to reveal this goal, some techniques were used as the structural analysis by X-ray diffraction (XRD) which a high intensity has been detected corresponds to the ZnO / NiO films with nickel chloride precursor, UV-Visible characterization depicts the presence of a maximum adsorption band appears in the ultraviolet range, the morphological characterization with Atomic Force Microscopy (AFM) reveals the roughness and the different grain size of particles, the big one of the latter agree, also, with to nickel chloride precursor used. The values of optical band gaps Eg are globally equal with high value noticeable agree with films that prepared with nickel chloride and zinc chloride precursors. The results obtained confirm the aim and a good agreement with the latter were found.

Physical and Magnetic Characterization of Hard/Soft SrFe12O19/CoFe2O4 Nanocomposite Magnets Made by Mechanical Alloying and Ultrasonic Irradiation

In this study, the particle sizes of SrFe12O19 in hard/soft SrFe12O19/CoFe2O4 nanocomposite magnets made using mechanical alloying and ultrasonic irradiation were investigated. SrFe12O19/CoFe2O4 nanocomposites were combined in a ratio of 75:25, with each magnetic material being prepared separately. SrFe12O19 powder was prepared from Fe2O3 and SrCO3 powder by mechanical alloying and ultrasonic irradiation for different times, 0, 3, 6, 9, and 12 h. Varying the ultrasonic time during the preparation of the SrFe12O19 samples resulted in differences in morphological characteristics, crystal structure, particle size, crystal size, microstrain, density, porosity, and magnetic properties. The longer the ultrasonic time, the crystal size and particle size decreases, the density increases, and the porosity reduction which affects the magnetic properties. SrFe12O19 after 12 h ultrasonic process reach Ms value = 61.29 emu/g. CoFe2O4 powder was produced from Fe2O3 and CoCO3 powder by mechanical alloying with a 10 h milling time. Furthermore, each SrFe12O19 sample was composited with CoFe2O4 powder by ultrasonic irradiation for 1 h and these composite samples also showed different characteristics, where there is an increase in Mr and Ms compared to the single SrFe12O19. The morphology, crystal structure, particle size, and magnetic properties of the samples were measured using scanning electron microscopy, X-ray diffraction, particle size analysis, and PERMAGRAPH. The crystal size and microstrain were calculated using a Williamson–Hall plot, and density and porosity were determined using Archimedes’ law.

Export Citation Format

Share document.

Journal of Nano Research

Number of papers	217
H4-Index
TQCC
Average citations	2.124
Median citations
Impact Factor	1.700 (based on 2022)

( API-Link )

Impact Factor : 1.700 (based on Web of Science 2022)

• # 283 / 321 (Q4) in Materials Science, Multidisciplinary
• # 94 / 101 (Q4) in Nanoscience & Nanotechnology
• # 127 / 150 (Q4) in Physics, Applied

Partner: • University Press Alert

Nanoscience and nanotechnology

Led by Nanoscale Research Letters, Nano-Micro Letters,  and Micro and Nano Systems Letters , our nano science journals offer homes for a wide range of nano science research and results. Ranging from the advanced imaging technologies and techniques underpinning nano science to nano biology, nano materials, and more, our journals include journals published with international partners as well as broad, comprehensive nano journals.

SpringerOpen celebrates National Nano Day 2017

We invite you to read our blog post about Nano Day; to listen to a mini-podcast from Wu Jiang, Deputy Editor of  Nanoscale Research Letters , and to visit the main Nano Day page at the National Nanotechnology Initiative . 

Featured journals

Speed 34 days from submission to first decision 23 days from acceptance to publication

Citation Impact 1.039 - Source Normalized Impact per Paper (SNIP) 0.862 - SCImago Journal Rank (SJR) 4.11 - CiteScore

Usage  30,869 downloads 884.0 Usage Factor

Social Media Impact 115 mentions

Speed 11 days from submission to first decision 14 days from acceptance to publication

Usage  24,294 downloads 886.0 Usage Factor

Social Media Impact 2 mentions

Speed 23 days from submission to first decision

Usage 125,300 downloads 736 Usage Factor 127 articles

Impact 4.849 2-year Impact Factor 3.641 5-year Impact Factor

Speed 29 days from submission to first decision 13 days from acceptance to publication

Usage  64,261 downloads 1076.5 Usage Factor

Social Media Impact 25 mentions

Nanoscale Research Letters

As a sample of what we publish, we’ve assembled a small selection of recent articles about TiO 2 here . 

Article Highlights

Radiotherapy has been, and will continue to be, a critical modality to treat cancer. Since the discovery of radiation-induced cytotoxicity in the late 19th century, both external and internal radiation sources have provided tremendous benefits to extend the life of cancer patients. Despite the dramatic improvement of radiation techniques, however, one challenge persists to limit the anti-tumor efficacy of radiotherapy, which is to maximize the deposited dose in tumor while sparing the rest of the healthy vital organs. Nanomedicine has stepped into the spotlight of cancer diagnosis and therapy during the past decades. Nanoparticles can potentiate radiotherapy by specifically delivering radionuclides or radiosensitizers into tumors, therefore enhancing the efficacy while alleviating the toxicity of radiotherapy. This paper reviews recent advances in synthetic nanoparticles for radiotherapy and radiosensitization, with a focus on the enhancement of in vivo anti-tumor activities. We also provide a brief discussion on radiation-associated toxicities as this is an area that, up to date, has been largely missing in the literature and should be closely examined in future studies involving nanoparticle-mediated radiosensitization.
In the field of regenerative medicine, stem cells are highly promising due to their innate ability to generate multiple types of cells that could replace/repair damaged parts of human organs and tissues. It has been reported that both in vitro and in vivo function/survival of stem cells could significantly be improved by utilizing functional materials such as biodegradable polymers, metal composites, nanopatterns and nanohybrid particles. Of various biocompatible materials available for use in stem cell-based therapy and research, carbon-based materials—including fullerenes graphene/graphene oxide and carbon nanotubes—have been found to possess unique physicochemical characteristics that contribute to the effective guidance of stem cell differentiation into specific lineages. In this review, we discuss a number of previous reports that investigated the use of carbon-based materials to control stem cell behavior, with a particular focus on their immense potential to guide the osteogenesis of mesenchymal stem cells (MSCs). We hope that this review will provide information on the full potential of using various carbon-based materials in stem cell-mediated regenerative therapy, particularly for bone regeneration and repair. †Contributed equally
We present a simple and scalable fluidic-assembly approach, in which bundles of single-walled carbon nanotubes (SWCNTs) are selectively aligned and deposited by directionally controlled dip-coating and solvent evaporation processes. The patterned surface with alternating regions of hydrophobic polydimethyl siloxane (PDMS) (height ~ 100 nm) strips and hydrophilic SiO  substrate was withdrawn vertically at a constant speed (~3 mm/min) from a solution bath containing SWCNTs (~0.1 mg/ml), allowing for directional evaporation and subsequent selective deposition of nanotube bundles along the edges of horizontally aligned PDMS strips. In addition, the fluidic assembly was applied to fabricate a field effect transistor (FET) with highly oriented SWCNTs, which demonstrate significantly higher current density as well as high turn-off ratio (T/O ratio ~ 100) as compared to that with randomly distributed carbon nanotube bundles (T/O ratio ~ <10).
Highly reactive integrated material systems have recently gained attention, as they promise a feasible tool for heterogeneous integration of micro electromechanical systems. As integrated energy sources they can be used to join heterogeneous materials without applying too much thermal stress to the whole device. An alternative approach is proposed, comprising a single layer of a reactive nanocomposite made of intermixed metal nanoparticles, instead of multilayer systems. In this study the development of the reactive nanocomposite from choice of materials through processing steps, handling and application methods are described. Eventually the results of the experiments upon the reactivity of the nanocomposites and the feasibility for bonding applications are presented. Analysis of the composites was performed by phase-analysis using x-ray diffraction and reaction propagation analysis by high-speed imaging. Composition of products was found to vary with initial particle sizes. Beside of other phases, the dominant phase was intermetallic NiAl.
The graphitic carbon nitride (g-C N ) which is a two-dimensional conjugated polymer has drawn broad interdisciplinary attention as a low-cost, metal-free, and visible-light-responsive photocatalyst in the area of environmental remediation. The g-C N -based materials have excellent electronic band structures, electron-rich properties, basic surface functionalities, high physicochemical stabilities and are “earth-abundant.” This review summarizes the latest progress related to the design and construction of g-C N -based materials and their applications including catalysis, sensing, imaging, and white-light-emitting diodes. An outlook on possible further developments in g-C N -based research for emerging properties and applications is also included.
...This paper gives a brief summary about the establishment and latest progress in the fundamental principle, updated progress and potential applications of [nanogenerator]-based self-powered gas sensing system. The development trend in this field is envisaged, and the basic configurations are also introduced.

How to Submit Your Manuscript

Your browser needs to have JavaScript enabled to view this video

• All subject areas
• Agricultural and Biological Sciences
• Arts and Humanities
• Biochemistry, Genetics and Molecular Biology
• Business, Management and Accounting
• Chemical Engineering
• Computer Science
• Decision Sciences
• Earth and Planetary Sciences
• Economics, Econometrics and Finance
• Engineering
• Environmental Science
• Health Professions
• Immunology and Microbiology
• Materials Science
• Mathematics
• Multidisciplinary
• Neuroscience
• Pharmacology, Toxicology and Pharmaceutics
• Physics and Astronomy
• Social Sciences
• All subject categories
• Acoustics and Ultrasonics
• Advanced and Specialized Nursing
• Aerospace Engineering
• Agricultural and Biological Sciences (miscellaneous)
• Agronomy and Crop Science
• Algebra and Number Theory
• Analytical Chemistry
• Anesthesiology and Pain Medicine
• Animal Science and Zoology
• Anthropology
• Applied Mathematics
• Applied Microbiology and Biotechnology
• Applied Psychology
• Aquatic Science
• Archeology (arts and humanities)
• Architecture
• Artificial Intelligence
• Arts and Humanities (miscellaneous)
• Assessment and Diagnosis
• Astronomy and Astrophysics
• Atmospheric Science
• Atomic and Molecular Physics, and Optics
• Automotive Engineering
• Behavioral Neuroscience
• Biochemistry
• Biochemistry, Genetics and Molecular Biology (miscellaneous)
• Biochemistry (medical)
• Bioengineering
• Biological Psychiatry
• Biomaterials
• Biomedical Engineering
• Biotechnology
• Building and Construction
• Business and International Management
• Business, Management and Accounting (miscellaneous)
• Cancer Research
• Cardiology and Cardiovascular Medicine
• Care Planning
• Cell Biology
• Cellular and Molecular Neuroscience
• Ceramics and Composites
• Chemical Engineering (miscellaneous)
• Chemical Health and Safety
• Chemistry (miscellaneous)
• Chiropractics
• Civil and Structural Engineering
• Clinical Biochemistry
• Clinical Psychology
• Cognitive Neuroscience
• Colloid and Surface Chemistry
• Communication
• Community and Home Care
• Complementary and Alternative Medicine
• Complementary and Manual Therapy
• Computational Mathematics
• Computational Mechanics
• Computational Theory and Mathematics
• Computer Graphics and Computer-Aided Design
• Computer Networks and Communications
• Computer Science Applications
• Computer Science (miscellaneous)
• Computer Vision and Pattern Recognition
• Computers in Earth Sciences
• Condensed Matter Physics
• Conservation
• Control and Optimization
• Control and Systems Engineering
• Critical Care and Intensive Care Medicine
• Critical Care Nursing
• Cultural Studies
• Decision Sciences (miscellaneous)
• Dental Assisting
• Dental Hygiene
• Dentistry (miscellaneous)
• Dermatology
• Development
• Developmental and Educational Psychology
• Developmental Biology
• Developmental Neuroscience
• Discrete Mathematics and Combinatorics
• Drug Discovery
• Drug Guides
• Earth and Planetary Sciences (miscellaneous)
• Earth-Surface Processes
• Ecological Modeling
• Ecology, Evolution, Behavior and Systematics
• Economic Geology
• Economics and Econometrics
• Economics, Econometrics and Finance (miscellaneous)
• Electrical and Electronic Engineering
• Electrochemistry
• Electronic, Optical and Magnetic Materials
• Emergency Medical Services
• Emergency Medicine
• Emergency Nursing
• Endocrine and Autonomic Systems
• Endocrinology
• Endocrinology, Diabetes and Metabolism
• Energy Engineering and Power Technology
• Energy (miscellaneous)
• Engineering (miscellaneous)
• Environmental Chemistry
• Environmental Engineering
• Environmental Science (miscellaneous)
• Epidemiology
• Experimental and Cognitive Psychology
• Family Practice
• Filtration and Separation
• Fluid Flow and Transfer Processes
• Food Animals
• Food Science
• Fuel Technology
• Fundamentals and Skills
• Gastroenterology
• Gender Studies
• Genetics (clinical)
• Geochemistry and Petrology
• Geography, Planning and Development
• Geometry and Topology
• Geotechnical Engineering and Engineering Geology
• Geriatrics and Gerontology
• Gerontology
• Global and Planetary Change
• Hardware and Architecture
• Health Informatics
• Health Information Management
• Health Policy
• Health Professions (miscellaneous)
• Health (social science)
• Health, Toxicology and Mutagenesis
• History and Philosophy of Science
• Horticulture
• Human Factors and Ergonomics
• Human-Computer Interaction
• Immunology and Allergy
• Immunology and Microbiology (miscellaneous)
• Industrial and Manufacturing Engineering
• Industrial Relations
• Infectious Diseases
• Information Systems
• Information Systems and Management
• Inorganic Chemistry
• Insect Science
• Instrumentation
• Internal Medicine
• Issues, Ethics and Legal Aspects
• Leadership and Management
• Library and Information Sciences
• Life-span and Life-course Studies
• Linguistics and Language
• Literature and Literary Theory
• LPN and LVN
• Management Information Systems
• Management, Monitoring, Policy and Law
• Management of Technology and Innovation
• Management Science and Operations Research
• Materials Chemistry
• Materials Science (miscellaneous)
• Maternity and Midwifery
• Mathematical Physics
• Mathematics (miscellaneous)
• Mechanical Engineering
• Mechanics of Materials
• Media Technology
• Medical and Surgical Nursing
• Medical Assisting and Transcription
• Medical Laboratory Technology
• Medical Terminology
• Medicine (miscellaneous)
• Metals and Alloys
• Microbiology
• Microbiology (medical)
• Modeling and Simulation
• Molecular Biology
• Molecular Medicine
• Nanoscience and Nanotechnology
• Nature and Landscape Conservation
• Neurology (clinical)
• Neuropsychology and Physiological Psychology
• Neuroscience (miscellaneous)
• Nuclear and High Energy Physics
• Nuclear Energy and Engineering
• Numerical Analysis
• Nurse Assisting
• Nursing (miscellaneous)
• Nutrition and Dietetics
• Obstetrics and Gynecology
• Occupational Therapy
• Ocean Engineering
• Oceanography
• Oncology (nursing)
• Ophthalmology
• Oral Surgery
• Organic Chemistry
• Organizational Behavior and Human Resource Management
• Orthodontics
• Orthopedics and Sports Medicine
• Otorhinolaryngology
• Paleontology
• Parasitology
• Pathology and Forensic Medicine
• Pathophysiology
• Pediatrics, Perinatology and Child Health
• Periodontics
• Pharmaceutical Science
• Pharmacology
• Pharmacology (medical)
• Pharmacology (nursing)
• Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
• Physical and Theoretical Chemistry
• Physical Therapy, Sports Therapy and Rehabilitation
• Physics and Astronomy (miscellaneous)
• Physiology (medical)
• Plant Science
• Political Science and International Relations
• Polymers and Plastics
• Process Chemistry and Technology
• Psychiatry and Mental Health
• Psychology (miscellaneous)
• Public Administration
• Public Health, Environmental and Occupational Health
• Pulmonary and Respiratory Medicine
• Radiological and Ultrasound Technology
• Radiology, Nuclear Medicine and Imaging
• Rehabilitation
• Religious Studies
• Renewable Energy, Sustainability and the Environment
• Reproductive Medicine
• Research and Theory
• Respiratory Care
• Review and Exam Preparation
• Reviews and References (medical)
• Rheumatology
• Safety Research
• Safety, Risk, Reliability and Quality
• Sensory Systems
• Signal Processing
• Small Animals
• Social Psychology
• Social Sciences (miscellaneous)
• Social Work
• Sociology and Political Science
• Soil Science
• Space and Planetary Science
• Spectroscopy
• Speech and Hearing
• Sports Science
• Statistical and Nonlinear Physics
• Statistics and Probability
• Statistics, Probability and Uncertainty
• Strategy and Management
• Stratigraphy
• Structural Biology
• Surfaces and Interfaces
• Surfaces, Coatings and Films
• Theoretical Computer Science
• Tourism, Leisure and Hospitality Management
• Transplantation
• Transportation
• Urban Studies
• Veterinary (miscellaneous)
• Visual Arts and Performing Arts
• Waste Management and Disposal
• Water Science and Technology
• All regions / countries
• Asiatic Region
• Eastern Europe
• Latin America
• Middle East
• Northern America
• Pacific Region
• Western Europe
• ARAB COUNTRIES
• IBEROAMERICA
• NORDIC COUNTRIES
• Afghanistan
• Bosnia and Herzegovina
• Brunei Darussalam
• Czech Republic
• Dominican Republic
• Netherlands
• New Caledonia
• New Zealand
• Papua New Guinea
• Philippines
• Puerto Rico
• Russian Federation
• Saudi Arabia
• South Africa
• South Korea
• Switzerland
• Syrian Arab Republic
• Trinidad and Tobago
• United Arab Emirates
• United Kingdom
• United States
• Vatican City State
• Book Series
• Conferences and Proceedings
• Trade Journals

• Citable Docs. (3years)
• Total Cites (3years)

-->

	Title	Type
1		journal	14.577 Q1	419	262	637	10044	17562	466	27.42	38.34	28.93
2		journal	9.191 Q1	640	2652	4816	205113	141178	4781	28.44	77.34	32.35
3		journal	6.484 Q1	116	239	609	23341	16977	608	29.81	97.66	34.55
4		journal	5.496 Q1	402	3240	6403	227642	125554	6369	18.99	70.26	33.52
5		journal	4.593 Q1	478	2057	5134	133225	83625	5091	15.41	64.77	33.30
6		journal	3.483 Q1	175	275	635	24164	9420	605	13.75	87.87	39.78
7		journal	3.411 Q1	550	1575	3877	73244	40031	3856	9.68	46.50	30.18
8		journal	3.348 Q1	294	3459	4300	231291	57031	4280	13.08	66.87	34.99
9		journal	3.016 Q1	435	389	1797	26953	24853	1797	13.06	69.29	40.56
10		journal	2.539 Q1	164	1543	2037	99401	21708	2027	10.92	64.42	37.30
11		journal	2.058 Q1	311	5109	17878	272179	159673	17856	8.33	53.27	34.37
12		journal	2.052 Q1	239	780	2387	44861	27387	2378	11.19	57.51	40.28
13		journal	1.840 Q1	109	478	1132	37071	12176	1131	10.46	77.55	41.81
14		journal	1.738 Q1	227	515	1730	18599	10537	1714	5.73	36.11	26.49
15		journal	1.660 Q1	277	1194	4876	61161	33684	4874	6.65	51.22	26.89
16		journal	1.586 Q1	252	1508	4756	76732	25006	4741	4.94	50.88	29.30
17		journal	1.571 Q1	97	77	220	11752	2017	219	8.30	152.62	34.55
18		journal	1.416 Q1	285	1687	5922	109910	36760	5909	5.76	65.15	34.18
19		journal	1.273 Q1	179	443	1559	33731	12840	1554	6.74	76.14	43.56
20		journal	1.246 Q2	246	394	1204	26666	7657	1193	6.12	67.68	34.87
21		journal	1.016 Q2	147	0	507	0	3296	507	5.85	0.00	0.00
22		journal	0.957 Q2	338	2489	8171	135898	28460	8136	3.32	54.60	29.37
23		journal	0.941 Q2	190	336	2149	19294	11018	2145	5.01	57.42	35.69
24		journal	0.902 Q2	103	149	567	4939	2386	566	4.12	33.15	18.91
25		journal	0.863 Q2	151	103	467	5846	2335	465	4.51	56.76	44.90
26		journal	0.848 Q2	35	5	26	302	170	26	5.53	60.40	61.11
27		journal	0.821 Q2	107	36	215	2378	934	210	3.69	66.06	43.62
28		journal	0.739 Q2	20	32	75	1477	336	74	3.88	46.16	24.82
29		journal	0.680 Q2	47	31	184	1457	425	171	2.33	47.00	16.41
30		journal	0.670 Q2	135	146	531	9430	2150	493	3.54	64.59	42.13
31		journal	0.659 Q2	73	119	198	4764	744	194	4.10	40.03	32.04
32		journal	0.631 Q2	228	771	3787	41379	11455	3786	2.98	53.67	32.77
33		journal	0.578 Q2	102	42	180	2220	656	177	3.08	52.86	32.16
34		journal	0.572 Q2	66	117	186	8811	734	186	3.73	75.31	27.29
35		journal	0.529 Q2	112	259	1348	12553	4336	1340	3.11	48.47	29.17
36		journal	0.524 Q2	101	113	1032	6025	3759	1023	3.37	53.32	25.23
37		journal	0.520 Q2	81	100	404	5515	1173	400	2.74	55.15	33.10
38		journal	0.516 Q2	78	65	254	5509	774	252	2.71	84.75	34.12
39		journal	0.512 Q2	54	45	219	2372	792	215	4.21	52.71	42.86
40		journal	0.503 Q3	111	104	395	4745	1111	393	2.69	45.63	27.27
41		journal	0.489 Q3	57	132	415	6259	1129	412	2.27	47.42	34.21
42		journal	0.476 Q3	145	139	502	5827	1206	502	2.61	41.92	24.56
43		journal	0.437 Q3	72	386	720	18594	2461	719	3.56	48.17	30.45
44		journal	0.435 Q3	94	110	344	3935	911	344	2.26	35.77	20.33
45		journal	0.416 Q3	142	255	867	15434	2121	864	2.10	60.53	39.69
46		journal	0.410 Q3	47	69	215	3048	590	214	2.60	44.17	28.38
47		journal	0.409 Q3	22	44	113	885	153	75	1.51	20.11	31.19
48		journal	0.394 Q3	105	315	1017	8834	1954	1012	1.85	28.04	24.83
49		journal	0.393 Q3	45	65	166	1617	309	142	1.78	24.88	19.70
50		journal	0.390 Q3	79	218	643	6780	1449	642	2.33	31.10	31.69

Follow us on @ScimagoJR Scimago Lab , Copyright 2007-2024. Data Source: Scopus®

Cookie settings

Cookie Policy

Legal Notice

Privacy Policy

Journal of Nanobiotechnology

• Most accessed
• Collections

ZnO NPs induce miR-342-5p mediated ferroptosis of spermatocytes through the NF-κB pathway in mice

Authors: Guangyu Liu, Jing Lv, Yifan Wang, Kaikai Sun, Huimin Gao, Yuanyou Li, Qichun Yao, Lizhu Ma, Gulzat Kochshugulova and Zhongliang Jiang

Zno nanoparticles: improving photosynthesis, shoot development, and phyllosphere microbiome composition in tea plants

Authors: Hao Chen, Yujie Song, Yu Wang, Huan Wang, Zhaotang Ding and Kai Fan

Nanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus

Authors: Haotian Yang, Meiqi Sun, He Qiu, Huiling Xu, Zhuofan Deng, Han Gu, Nan Wang, Liuyang Du, Fushan Shi, Jiyong Zhou and Fang He

NIR-responsive electrospun nanofiber dressing promotes diabetic-infected wound healing with programmed combined temperature-coordinated photothermal therapy

Authors: Jinlang Fu, Ding Wang, Zinan Tang, Yixin Xu, Jiajun Xie, Rong Chen, Pinkai Wang, Qiang Zhong, Yanhong Ning, Mingyuan Lei, Huaming Mai, Hao Li, Haibing Liu, Jian Wang and Hao Cheng

Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury

Authors: Wan-ting Meng, Jing Zhu, Ya-chao Wang, Chang-le Shao, Xiu-ya Li, Ping-ping Lu, Meng-ying Huang, Fang-fang Mou, Hai-dong Guo and Guang Ji

Most recent articles RSS

View all articles

Nano based drug delivery systems: recent developments and future prospects

Authors: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Estefania Vangelie Ramos Campos, Maria del Pilar Rodriguez-Torres, Laura Susana Acosta-Torres, Luis Armando Diaz-Torres, Renato Grillo, Mallappa Kumara Swamy, Shivesh Sharma, Solomon Habtemariam and Han-Seung Shin

Applications of nanoparticles in biology and medicine

Authors: OV Salata

Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy

Authors: Savita Bisht, Georg Feldmann, Sheetal Soni, Rajani Ravi, Collins Karikar, Amarnath Maitra and Anirban Maitra

‘Green’ synthesis of metals and their oxide nanoparticles: applications for environmental remediation

Authors: Jagpreet Singh, Tanushree Dutta, Ki-Hyun Kim, Mohit Rawat, Pallabi Samddar and Pawan Kumar

Nanoparticles – known and unknown health risks

Authors: Peter HM Hoet, Irene Brüske-Hohlfeld and Oleg V Salata

Most accessed articles RSS

Nanotechnologies for lymph nodes imaging and target delivery Collection published: 7 April 2023

Advances in Nanomaterials for Gene Therapy and Genome Editing Collection published: 16 March 2023

Women in Nanobiotechnology Collection published: 5 March 2022

Towards nanotechnology in agrifood sciences Collection published: 24 February 2021

Inorganic nanoparticles and cellular mechanobiology: from nanotoxicology to cytoskeleton-targeting nanotheranostics Journal of Nanobiotechnology Collection published: 18 November 2020

Nanosensors: their potential use in the life sciences and clinical medicine Journal of Nanobiotechnology Collection published: 28 October 2019

Swiss National Research Programme “Opportunities and risks of nanomaterials” (NRP 64) Journal of Nanobiotechnology Collection published: 13 July 2017

Highlights from the acoustofluidic conference 2012 - a conference on particle and fluid manipulation with ultrasound Journal of Nanobiotechnology Collection published: 28 June 2013

Latest Tweets

Your browser needs to have JavaScript enabled to view this timeline

Article of the Year Awards

Do you have an idea for a thematic series? Let us know!

Aims and scope.

Journal of Nanobiotechnology is an open access peer-reviewed journal communicating scientific and technological advances in the fields of medicine and biology, with an emphasis in their interface with nanoscale sciences. The journal provides biomedical scientists and the international biotechnology business community with the latest developments in the growing field of Nanobiotechnology. For a list of sections in the journal, please click here .

The 2024 Journal of Nanobiotechnology (JNB) Trailblazer Award is now open for nominations!

Please click here to read more.

2024 Rising Star winners

We are delighted to announce the winners of the 2024 Rising Star Awards: César de la Fuente, Dalong Ni, Yang Shi, Amirali Popat

Call for papers: Women in Nanobiotechnology

The Editors-in-Chief of  Journal of Nanobiotechnology  and Guest Editors invite submissions to a collection from Women in Nanobiotechnology .  Read more.

Featured collection: Towards nanotechnology in agrifood sciences

The Editors-in-Chief of  J Nanobiotechnology and the guest editors, Leonardo Fernandes Fraceto and Viviana Scognamiglio present a special collection entitled Towards nanotechnology in agrifood sciences   Read more .

Professor Weibo Cai (Editor-in-Chief)

Professor Cai is Vilas Distinguished Achievement Professor of Radiology, Medical Physics, Materials Science & Engineering, and Pharmaceutical Sciences at the University of Wisconsin - Madison, USA. Dr. Cai’s research at UW-Madison ( http://mi.wisc.edu ) is primarily focused on molecular imaging and nanobiotechnology. Dr. Cai has authored >400 peer-reviewed articles (total citation: > 40000; h-index: 106) and received many awards, including the European Association of Nuclear Medicine (EANM) Springer Prize (2011 & 2013), American Cancer Society Research Scholar (2013), Inaugural Nano Research Young Innovators (NR45) in Nanobiotechnology Award (2018), Highly Cited Researchers from Clarivate Analytics (Cross-Field, 2018), Fellow of the American Institute for Medical and Biological Engineering (AIMBE, 2018), Fellow of the Society of Nuclear Medicine and Molecular Imaging (SNMMI, 2019), Fellow of the Royal Society of Chemistry (RSC, 2021), SNMMI Radiopharmaceutical Sciences Council Michael J. Welch Award (2022), BMC/Springer Nature Journal of Nanobiotechnology Trailblazer Award (2022), among many others. What Dr. Cai is most proud of is that his trainees (more than 70, from more than a dozen countries) at UW - Madison have received >150 awards to date, such as 2012 SNMMI Berson-Yalow Award and more than a dozen SNMMI Young Investigator Awards, among others. To date, more than 15 of Dr. Cai’s trainees have started independent research groups at world-class universities. 

• Editorial Board
• Manuscript editing services
• Instructions for Editors
• Sign up for article alerts and news from this journal

Annual Journal Metrics

Citation Impact 2023 Journal Impact Factor: 10.6 5-year Journal Impact Factor: 11.4 Source Normalized Impact per Paper (SNIP): 1.296 SCImago Journal Rank (SJR): 1.840

Speed 2023 Submission to first editorial decision (median days): 4 Submission to acceptance (median days): 85

Usage 2023 Downloads: 2,763,562 Altmetric mentions: 1,483

• More about our metrics
• Follow us on Twitter

ISSN: 1477-3155

• Submission enquiries: [email protected]

Identifiers

Linking ISSN (ISSN-L): 1661-9889

URL https://www.scientific.net/JNanoR

Google https://www.google.com/search?q=ISSN+%221661-9897%22

Bing https://www.bing.com/search?q=ISSN+%221661-9897%22

Yahoo https://search.yahoo.com/search?p=ISSN%20%221661-9897%22

Helveticat https://nb-helveticat.primo.exlibrisgroup.com/discovery/search?query=issn,contains,1661-9897&tab=LibraryCatalog&search_scope=Helveticat&vid=41SNL_51_INST:helveticat&lang=en

Resource information

Archival status.

Title proper: Journal of nano research.

Other variant title: JNanoR

Country: Switzerland

Medium: Online

Status	Publisher	Keeper	From	To	Updated	Extent of archive
Preserved	Trans Tech Publications	CLOCKSS Archive	2016	2024	01/07/2024
Preserved	Trans Tech Publications Ltd.	Portico	2008	2024	02/07/2024

Record information

Last modification date: 12/02/2022

Type of record: Confirmed

ISSN Center responsible of the record: ISSN National Centre for Switzerland Please contact this ISSN Centre by clicking on it for any request or query concerning the publication

downloads requested

Discover all the features of the complete ISSN records

Display mode x.

Labelled view

MARC21 view

UNIMARC view

ACS Publications Workshop

Acs nano summit 2024: emerging materials for future nanotechnology.

Register Now

Hybrid event

Jul 4, 2024 | 9 AM–6 PM GMT+09:00

Nano Materials Science

Brought to you by:

ACS Nano Summit 2024: Emerging Materials for Future Nanotechnology will provide an unparalleled opportunity for global colleagues to reconnect and engage in discussions on the latest scientific breakthroughs, technological advancements, and emerging trends in the field. The distinguished conference will include keynote presentations by ACS Nano editors, who will lead themed sessions and encourage stimulating discussions on the growing challenges in the field.

Featuring ACS Editors Keynote and Invited Talks, as well as ACS Lectureship and Impact Awards Lecture, this session promises insightful discussions and innovative perspectives on the evolving world of nanomaterials. Join us as we unravel the potential of emerging materials in driving advancements and revolutionizing nanotechnology as we know it.

• Room 210, Exhibition Center I, KINTEX 217-60, Kintex-ro, Ilsanseo-gu, Goyang-si, Gyeonggi-do, South Korea

Related Events:

Acs publications summit: global trends in materials and nanotechnology, la creación de materiales macroscópicos a través del ensamblaje de nanotubos de boro nitruro, creating circular economies: catalysis challenges and opportunities in sustainable chemistry, accounts of chemical research journal club, nanoscience global webinar series, acs institute.

Keep learning. Excel in your career.

Choose from more than 200 courses in seven different categories, taught by experts in the chemistry community, online and in person.

Explore the ACS Institute

Accept & Close The ACS takes your privacy seriously as it relates to cookies. We use cookies to remember users, better understand ways to serve them, improve our value proposition, and optimize their experience. Learn more about managing your cookies at Cookies Policy .

• Terms of Use
• Accessibility

Copyright © 2024 American Chemical Society

Information

• Author Services

Initiatives

You are accessing a machine-readable page. In order to be human-readable, please install an RSS reader.

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess .

Feature papers represent the most advanced research with significant potential for high impact in the field. A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications.

Feature papers are submitted upon individual invitation or recommendation by the scientific editors and must receive positive feedback from the reviewers.

Editor’s Choice articles are based on recommendations by the scientific editors of MDPI journals from around the world. Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal.

Original Submission Date Received: .

• Active Journals
• Find a Journal
• Proceedings Series
• For Authors
• For Reviewers
• For Editors
• For Librarians
• For Publishers
• For Societies
• For Conference Organizers
• Open Access Policy
• Institutional Open Access Program
• Special Issues Guidelines
• Editorial Process
• Research and Publication Ethics
• Article Processing Charges
• Testimonials
• Preprints.org
• SciProfiles
• Encyclopedia

Article Menu

• Subscribe SciFeed
• Recommended Articles
• Google Scholar
• on Google Scholar
• Table of Contents

Find support for a specific problem in the support section of our website.

Please let us know what you think of our products and services.

Visit our dedicated information section to learn more about MDPI.

JSmol Viewer

Nano-based approaches in surface modifications of dental implants: a literature review.

1. Introduction

3. nanomaterials in implantology, 3.1. nanotubes, 3.2. nanopores, 3.3. metal nanoparticles, 3.4. silica nanoparticles, 3.5. hydroxyapatite, 3.6. carbon nanoparticles, 3.7. biopolymers, 4. enhancement of implant integration, 4.1. tnts for enhancement of soft and hard tissue integration, 4.2. tnts for osteoporosis, 4.3. tnts for alleviation of diabetes, 4.4. other nanomaterials, 5. immunomodulation strategies, 5.1. non-biofouling strategies, 5.2. anti-inflammatory drug loading, 6. prevention of peri-implantitis, 6.1. nps with inherent antibacterial properties, 6.2. nps loaded with drugs, 6.3. chitosan hybrid coatings, 6.4. other nanomaterials, 7. corrosion resistance, 8. future perspectives, author contributions, institutional review board statement, informed consent statement, data availability statement, conflicts of interest.

• Buser, D.; Chappuis, V.; Belser, U.C.; Chen, S. Implant placement post extraction in esthetic single tooth sites: When immediate, when early, when late? Periodontol. 2000 2017 , 73 , 84–102. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Branemark, P.I.; Adell, R.; Breine, U.; Hansson, B.O.; Lindstrom, J.; Ohlsson, A. Intra-osseous anchorage of dental prostheses: I. Experimental studies. Scand. J. Plast. Reconstr. Surg. 1969 , 3 , 81–100. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Ogle, O.E. Implant surface material, design, and osseointegration. Dent. Clin. N. Am. 2015 , 59 , 505–520. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Coelho, P.G.; Granjeiro, J.M.; Romanos, G.E.; Suzuki, M.; Silva, N.R.; Cardaropoli, G.; Thompson, V.P.; Lemons, J.E. Basic research methods and current trends of dental implant surfaces. J. Biomed. Mater. Res. B Appl. Biomater. 2009 , 88 , 579–596. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Gaviria, L.; Salcido, J.P.; Guda, T.; Ong, J.L. Current trends in dental implants. J. Korean Assoc. Oral Maxillofac. Surg. 2014 , 40 , 50–60. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Variola, F.; Yi, J.H.; Richert, L.; Wuest, J.D.; Rosei, F.; Nanci, A. Tailoring the surface properties of Ti6Al4V by controlled chemical oxidation. Biomaterials 2008 , 29 , 1285–1298. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Mendonça, G.; Mendonça, D.B.; Aragão, F.J.; Cooper, L.F. Advancing dental implant surface technology--from micron- to nanotopography. Biomaterials 2008 , 29 , 3822–3835. [ Google Scholar ] [ CrossRef ]
• Webster, T.J.; Ergun, C.; Doremus, R.H.; Siegel, R.W.; Bizios, R. Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics. J. Biomed. Mater. Res. 2000 , 51 , 475–483. [ Google Scholar ] [ CrossRef ]
• Colon, G.; Ward, B.C.; Webster, T.J. Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO 2 . J. Biomed. Mater. Res. A 2006 , 78 , 595–604. [ Google Scholar ] [ CrossRef ]
• Rasouli, R.; Barhoum, A.; Uludag, H. A review of nanostructured surfaces and materials for dental implants: Surface coating, patterning and functionalization for improved performance. Biomater. Sci. 2018 , 6 , 1312–1338. [ Google Scholar ] [ CrossRef ]
• Valamvanos, T.-F.; Dereka, X.; Katifelis, H.; Gazouli, M.; Lagopati, N. Recent Advances in Scaffolds for Guided Bone Regeneration. Biomimetics 2024 , 9 , 153. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Yang, J.; Zhang, H.; Chan, S.M.; Li, R.; Wu, Y.; Cai, M.; Wang, A.; Wang, Y. TiO 2 Nanotubes Alleviate Diabetes-Induced Osteogenetic Inhibition. Int. J. Nanomed. 2020 , 15 , 3523–3537. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• De Avila, E.D.; Van Oirschot, B.A.; Van den Beucken, J.J.J.P. Biomaterial-based possibilities for managing peri-implantitis. J. Periodontal Res. 2020 , 55 , 165–173. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Gulati, K.; Chopra, D.; Kocak-Oztug, N.A.; Verron, E. Fit and forget: The future of dental implant therapy via nanotechnology. Adv. Drug Deliv. Rev. 2023 , 199 , 114900. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Kunrath, M.F.; Shah, F.A.; Dahlin, C. Bench-to-bedside: Feasibility of nano-engineered and drug-delivery biomaterials for bone-anchored implants and periodontal applications. Mater. Today Bio 2022 , 18 , 100540. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Demetzos, C. Pharmaceutical Nanotechnology Fundamentals and Practical Applications ; Adis: Singapore, 2018. [ Google Scholar ]
• Chopra, D.; Gulati, K.; Ivanovski, S. Understanding and optimizing the antibacterial functions of anodized nano-engineered titanium implants. Acta Biomater. 2021 , 127 , 80–101. [ Google Scholar ] [ CrossRef ]
• Lee, J.K.; Choi, D.S.; Jang, I.; Choi, W.Y. Improved osseointegration of dental titanium implants by TiO 2 nanotube arrays with recombinant human bone morphogenetic protein-2: A pilot in vivo study. Int. J. Nanomed. 2015 , 10 , 1145–1154. [ Google Scholar ]
• Zhang, Y.; Gulati, K.; Li, Z.; Di, P.; Liu, Y. Dental Implant Nano-Engineering: Advances, Limitations and Future Directions. Nanomaterials 2021 , 11 , 2489. [ Google Scholar ] [ CrossRef ]
• Bapat, R.A.; Chaubal, T.V.; Joshi, C.P.; Bapat, P.R.; Choudhury, H.; Pandey, M.; Gorain, B.; Kesharwani, P. An overview of application of silver nanoparticles for biomaterials in dentistry. Mater. Sci. Eng. C Mater. Biol. Appl. 2018 , 91 , 881–898. [ Google Scholar ] [ CrossRef ]
• Roco, M.C. Nanoscale Science and Engineering: Unifying and Transforming Tools. AIChE J. 2004 , 50 , 890–897. [ Google Scholar ] [ CrossRef ]
• Abdulkareem, E.H.; Memarzadeh, K.; Allaker, R.P.; Huang, J.; Pratten, J.; Spratt, D. Anti-biofilm activity of zinc oxide and hydroxyapatite nanoparticles as dental implant coating materials. J. Dent. 2015 , 43 , 1462–1469. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Vagena, I.-A.; Gatou, M.-A.; Theocharous, G.; Pantelis, P.; Gazouli, M.; Pippa, N.; Gorgoulis, V.G.; Pavlatou, E.A.; Lagopati, N. Functionalized ZnO-Based Nanocomposites for Diverse Biological Applications: Current Trends and Future Perspectives. Nanomaterials 2024 , 14 , 397. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Huang, Y.; Li, P.; Zhao, R.; Zhao, L.; Liu, J.; Peng, S.; Fu, X.; Wang, X.; Luo, R.; Wang, R.; et al. Silica nanoparticles: Biomedical applications and toxicity. Biomed. Pharmacother. 2022 , 151 , 113053. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Chen, L.; Zhou, X.; He, C. Mesoporous silica nanoparticles for tissue-engineering applications. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2019 , 11 , e1573. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Abraham, C.M. A brief historical perspective on dental implants, their surface coatings and treatments. Open Dent. J. 2014 , 8 , 50–55. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Lagopati, N.; Agathopoulos, S. Hydroxyapatite Scaffolds Produced from Cuttlefish Bone via Hydrothermal Transformation for Application in Tissue Engineering and Drug Delivery Systems. In Marine-Derived Biomaterials for Tissue Engineering Applications ; Choi, A., Ben-Nissan, B., Eds.; Springer Series in Biomaterials Science and Engineering; Springer: Singapore, 2019; Volume 14. [ Google Scholar ]
• Almeida, D.; Sartoretto, S.C.; Calasans-Maia, J.A.; Ghiraldini, B.; Bezerra, F.J.B.; Granjeiro, J.M.; Calasans-Maia, M.D. In vivo osseointegration evaluation of implants coated with nanostructured hydroxyapatite in low density bone. PLoS ONE 2023 , 18 , 0282067. [ Google Scholar ] [ CrossRef ]
• Zhou, W.; Liu, Z.; Xu, S.; Hao, P.; Xu, F.; Sun, A. Long-term survivability of hydroxyapatite-coated implants: A meta-analysis. Oral Surg. 2011 , 4 , 2–7. [ Google Scholar ] [ CrossRef ]
• Jang, W.; Kim, H.S.; Alam, K.; Ji, M.K.; Cho, H.S.; Lim, H.P. Direct-Deposited Graphene Oxide on Dental Implants for Antimicrobial Activities and Osteogenesis. Int. J. Nanomed. 2021 , 16 , 5745–5754. [ Google Scholar ] [ CrossRef ]
• Di Carlo, R.; Di Crescenzo, A.; Pilato, S.; Ventrella, A.; Piattelli, A.; Recinella, L.; Chiavaroli, A.; Giordani, S.; Baldrighi, M.; Camisasca, A.; et al. Osteoblastic Differentiation on Graphene Oxide-Functionalized Titanium Surfaces: An In Vitro Study. Nanomaterials 2020 , 10 , 654. [ Google Scholar ] [ CrossRef ]
• López-Valverde, N.; Aragoneses, J.; López-Valverde, A.; Rodríguez, C.; Macedo de Sousa, B.; Aragoneses, J.M. Role of chitosan in titanium coatings. trends and new generations of coatings. Front. Bioeng. Biotechnol. 2022 , 10 , 907589. [ Google Scholar ] [ CrossRef ]
• Gulati, K.; Ivanovski, S. Dental implants modified with drug releasing titania nanotubes: Therapeutic potential and developmental challenges. Expert Opin. Drug. Deliv. 2017 , 14 , 1009–1024. [ Google Scholar ] [ CrossRef ]
• Balasundaram, G.; Yao, C.; Webster, T.J. TiO 2 nanotubes functionalized with regions of bone morphogenetic protein-2 increases osteoblast adhesion. J. Biomed. Mater. Res. A 2008 , 84 , 447–453. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Kodama, A.; Bauer, S.; Komatsu, A.; Asoh, H.; Ono, S.; Schmuki, P. Bioactivation of titanium surfaces using coatings of TiO(2) nanotubes rapidly pre-loaded with synthetic hydroxyapatite. Acta Biomater. 2009 , 5 , 2322–2330. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Liu, X.; Zhou, X.; Li, S.; Lai, R.; Zhou, Z.; Zhang, Y.; Zhou, L. Effects of titania nanotubes with or without bovine serum albumin loaded on human gingival fibroblasts. Int. J. Nanomed. 2014 , 9 , 1185–1198. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Lee, S.J.; Oh, T.J.; Bae, T.S.; Lee, M.H.; Soh, Y.; Kim, B.I.; Kim, H.S. Effect of bisphosphonates on anodized and heat-treated titanium surfaces: An animal experimental study. J. Periodontol. 2011 , 82 , 1035–1042. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Shen, X.; Ma, P.; Hu, Y.; Gaoqiang, X.; Xu, K.; Chen, W.; Ran, Q.; Dai, L.; Yu, Y.; Mu, C.; et al. Alendronate-loaded hydroxyapatite-TiO 2 nanotubes for improved bone formation in osteoporosis rabbits. J. Mater. Chem. B 2016 , 4 , 1423–1436. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Khan, A.A.; Sándor, G.K.; Dore, E.; Morrison, A.D.; Alsahli, M.; Amin, F.; Peters, E.; Hanley, D.A.; Chaudry, S.R.; Lentle, B.; et al. Canadian Taskforce on Osteonecrosis of the Jaw. Bisphosphonate associated osteonecrosis of the jaw. J. Rheumatol. 2009 , 36 , 478–490. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Zhang, W.; Jin, Y.; Qian, S.; Li, J.; Chang, Q.; Ye, D.; Pan, H.; Zhang, M.; Cao, H.; Liu, X.; et al. Vacuum extraction enhances rhPDGF-BB immobilization on nanotubes to improve implant osseointegration in ovariectomized rats. Nanomedicine 2014 , 10 , 1809–1818. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Lee, Y.H.; Bhattarai, G.; Park, I.S.; Kim, G.R.; Kim, G.E.; Lee, M.H.; Yi, H.K. Bone regeneration around N-acetyl cysteine-loaded nanotube titanium dental implant in rat mandible. Biomaterials 2013 , 34 , 10199–10208. [ Google Scholar ] [ CrossRef ]
• Zhang, X.; Zhang, X.; Wang, B.; Lan, J.; Yang, H.; Wang, Z.; Chang, X.; Wang, S.; Ma, X.; Qiao, H.; et al. Synergistic effects of lanthanum and strontium to enhance the osteogenic activity of TiO 2 nanotube biological interface. Ceram. Int. 2020 , 46 , 13969–13979. [ Google Scholar ] [ CrossRef ]
• de Araújo Nobre, M.; Maló, P.; Gonçalves, Y.; Sabas, A.; Salvado, F. Dental implants in diabetic patients: Retrospective cohort study reporting on implant survival and risk indicators for excessive marginal bone loss at 5 years. J. Oral Rehabil. 2016 , 43 , 863–870. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Chambrone, L.; Palma, L.F. Current status of dental implants survival and peri-implant bone loss in patients with uncontrolled type-2 diabetes mellitus. Curr. Opin. Endocrinol. Diabetes Obes. 2019 , 26 , 219–222. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Lee, Y.H.; Kim, J.S.; Kim, J.E.; Lee, M.H.; Jeon, J.G.; Park, I.S.; Yi, H.K. Nanoparticle mediated PPARγ gene delivery on dental implants improves osseointegration via mitochondrial biogenesis in diabetes mellitus rat model. Nanomedicine 2017 , 13 , 1821–1832. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Fang, K.; Song, W.; Wang, L.; Jia, S.; Wei, H.; Ren, S.; Xu, X.; Song, Y. Immobilization of chitosan film containing semaphorin 3A onto a microarc oxidized titanium implant surface via silane reaction to improve MG63 osteogenic differentiation. Int. J. Nanomed. 2014 , 9 , 4649–4657. [ Google Scholar ]
• Yamada, M.; Ueno, T.; Tsukimura, N.; Ikeda, T.; Nakagawa, K.; Hori, N.; Suzuki, T.; Ogawa, T. Bone integration capability of nanopolymorphic crystalline hydroxyapatite coated on titanium implants. Int. J. Nanomed. 2012 , 7 , 859–873. [ Google Scholar ]
• Zhao, S.F.; Jiang, Q.H.; Peel, S.; Wang, X.X.; He, F.M. Effects of magnesium-substituted nanohydroxyapatite coating on implant osseointegration. Clin. Oral Implants Res. 2013 , 24 (Suppl. A100), 34–41. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Heo, D.N.; Ko, W.K.; Lee, H.R.; Lee, S.J.; Lee, D.; Um, S.H.; Lee, J.H.; Woo, Y.H.; Zhang, L.G.; Lee, D.W.; et al. Titanium dental implants surface-immobilized with gold nanoparticles as osteoinductive agents for rapid osseointegration. J. Colloid Interface Sci. 2016 , 1 , 129–137. [ Google Scholar ] [ CrossRef ]
• Qiao, S.; Cao, H.; Zhao, X.; Lo, H.; Zhuang, L.; Gu, Y.; Shi, J.; Liu, X.; Lai, H. Ag-plasma modification enhances bone apposition around titanium dental implants: An animal study in Labrador dogs. Int. J. Nanomed. 2015 , 10 , 653–664. [ Google Scholar ]
• Bartkowiak, A.; Suchanek, K.; Menaszek, E.; Szaraniec, B.; Lekki, J.; Perzanowski, M.; Marszałek, M. Biological effect of hydrothermally synthesized silica nanoparticles within crystalline hydroxyapatite coatings for titanium implants. Mater. Sci. Eng. C Mater. Biol. Appl. 2018 , 92 , 88–95. [ Google Scholar ] [ CrossRef ]
• Jo, Y.K.; Choi, B.H.; Kim, C.S.; Cha, H.J. Diatom-Inspired Silica Nanostructure Coatings with Controllable Microroughness Using an Engineered Mussel Protein Glue to Accelerate Bone Growth on Titanium-Based Implants. Adv. Mater. 2017 , 29 , 46. [ Google Scholar ] [ CrossRef ]
• Covarrubias, C.; Mattmann, M.; Von Marttens, A.; Caviedes, P.; Arriagadac, C.; Valenzuelaa, F.; Rodríguez, J.P.; Corral Núñez, C. Osseointegration properties of titanium dental implants modified with a nanostructured coating based on ordered porous silica and bioactive glass nanoparticles. Appl. Surf. Sci. 2016 , 363 , 286–295. [ Google Scholar ] [ CrossRef ]
• Vandamme, K.; Thevissen, K.; Mesquita, M.F.; Coropciuc, R.G.; Agbaje, J.; Thevissen, P.; da Silva, W.J.; Vleugels, J.; De Cremer, K.; Gerits, E.; et al. Implant functionalization with mesoporous silica: A promising antibacterial strategy, but does such an implant osseointegrate? Clin. Exp. Dent. Res. 2021 , 7 , 502–511. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Frankenberger, T.; Graw, C.L.; Engel, N.; Gerber, T.; Frerich, B.; Dau, M. Sustainable Surface Modification of Polyetheretherketone (PEEK) Implants by Hydroxyapatite/Silica Coating-An In Vivo Animal Study. Materials 2021 , 14 , 4589. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Frandsen, C.J.; Brammer, K.S.; Noh, K.; Connelly, L.; Oh, S.; Chen, L.-H.; Jin, S. Zirconium oxide nanotube surface prompts increased osteoblast functionality and mineralization. Mater. Sci. Eng. 2011 , 31 , 1716–1722. [ Google Scholar ] [ CrossRef ]
• Wang, C.; Hu, H.; Li, Z.; Shen, Y.; Xu, Y.; Zhang, G.; Zeng, X.; Deng, J.; Zhao, S.; Ren, T.; et al. Enhanced Osseointegration of Titanium Alloy Implants with Laser Microgrooved Surfaces and Graphene Oxide Coating. ACS Appl. Mater. Interfaces 2019 , 11 , 39470–39483. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Tallarico, M.; Baldini, N.; Gatti, F.; Martinolli, M.; Xhanari, E.; Meloni, S.M.; Gabriele, C.; Immacolata, L.A. Role of New Hydrphilic Surfaces on Early Success Rate and Implant Stability: 1-Year Post-loading Results of a Multicenter, Split-Mouth, Randomized Controlled Trial. Eur. J. Dent. 2021 , 15 , 1–7. [ Google Scholar ] [ PubMed ]
• Tallarico, M.; Gatti, F.; Xhanari, E.; Muzzi, L.; Gheorghita, M.; de Waal, A.; Deliverska, E.; Widmer, N.; Melodia, D.; Ceruso, F.M.; et al. A split-mouth, multicentre randomized controlled trial comparing single sandblasted acidetched implants with or without surface modified with ph buffering agent: Results one year after loading. Clin. Trials Dent. 2023 , 5 , 29. [ Google Scholar ] [ CrossRef ]
• Zhang, J.; Bai, H.; Bai, M.; Wang, X.; Li, Z.; Xue, H.; Wang, J.; Cui, Y.; Wang, H.; Wang, Y.; et al. Bisphosphonate-incorporated coatings for orthopedic implants functionalization. Mater. Today Bio 2023 , 22 , 100737. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Trindade, R.; Albrektsson, T.; Tengvall, P.; Wennerberg, A. Foreign Body Reaction to Biomaterials: On Mechanisms for Buildup and Breakdown of Osseointegration. Clin. Implant. Dent. Relat. Res. 2016 , 18 , 192–203. [ Google Scholar ] [ CrossRef ]
• Eren, T.; Baysal, G.; Doğan, F. Biocidal Activity of Bone Cements Containing Curcumin and Pegylated Quaternary Polyethylenimine. J. Polym. Environ. 2020 , 28 , 2469–2480. [ Google Scholar ] [ CrossRef ]
• Amengual-Peñafiel, L.; Córdova, L.A.; Constanza Jara-Sepúlveda, M.; Brañes-Aroca, M.; Marchesani-Carrasco, F.; Cartes-Velásquez, R. Osteoimmunology drives dental implant osseointegration: A new paradigm for implant dentistry. Jpn. Dent. Sci. Rev. 2021 , 57 , 12–19. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Kang, S.M.; Kong, B.; Oh, E.; Choi, J.S.; Choi, I.S. Osteoconductive conjugation of bone morphogenetic protein-2 onto titanium/titanium oxide surfaces coated with non-biofouling poly(poly(ethylene glycol) methacrylate). Colloids Surf. B Biointerfaces 2010 , 75 , 385–389. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Smith, B.S.; Capellato, P.; Kelley, S.; Gonzalez-Juarrero, M.; Popat, K.C. Reduced in vitro immune response on titania nanotube arrays compared to titanium surface. Biomater. Sci. 2013 , 1 , 322–332. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Neacsu, P.; Mazare, A.; Schmuki, P.; Cimpean, A. Attenuation of the macrophage inflammatory activity by TiO 2 nanotubes via inhibition of MAPK and NF-κB pathways. Int. J. Nanomed. 2015 , 10 , 6455–6467. [ Google Scholar ]
• Gulati, K.; Moon, H.J.; Li, T.; Sudheesh Kumar, P.T.; Ivanovski, S. Titania nanopores with dual micro-/nano-topography for selective cellular bioactivity. Mater. Sci. Eng. C Mater. Biol. Appl. 2018 , 91 , 624–630. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Li, R.; Zhang, H.; Yao, X.; Tang, B.; Chu, P.; Zhang, X. Regulation of TiO 2 nanoarrays on titanium implants for enhanced osteogenic activity and immunomodulation. J. Mater. Sci. Technol. 2023 , 150 , 233–244. [ Google Scholar ] [ CrossRef ]
• Su, J.; Du, Z.; Xiao, L.; Wei, F.; Yang, Y.; Li, M.; Qiu, Y.; Liu, J.; Chen, J.; Xiao, Y. Graphene oxide coated Titanium Surfaces with Osteoimmunomodulatory Role to Enhance Osteogenesis. Mater. Sci. Eng. C Mater. Biol. Appl. 2020 , 113 , 110983. [ Google Scholar ] [ CrossRef ] [ PubMed ]
• Li, B.; Zhang, L.; Wang, D.; Liu, X.; Li, H.; Liang, C.; Zhao, X. Thermo-sensitive hydrogel on anodized titanium surface to regulate immune response. Surf. Coat. Technol. 2020 , 405 , 126624. [ Google Scholar ] [ CrossRef ]
• Chen, D.; Yu, C.; Ying, Y.; Luo, Y.; Ren, L.; Zhu, C.; Yang, K.; Wu, B.; Liu, Q. Study of the Osteoimmunomodulatory Properties of Curcumin-Modified Copper-Bearing Titanium. Molecules 2022 , 27 , 3205. [ Google Scholar ] [ CrossRef ]
• Liu, J.; Shi, Y.; Zhao, Y.; Liu, Y.; Yang, X.; Li, K.; Zhao, W.; Han, J.; Li, J.; Ge, S. A Multifunctional Metal-Phenolic Nanocoating on Bone Implants for Enhanced Osseointegration via Early Immunomodulation. Adv. Sci. 2024 , 11 , e2307269. [ Google Scholar ] [ CrossRef ]
• Doadrio, A.L.; Conde, A.; Arenas, M.A.; Hernández-López, J.M.; de Damborenea, J.J.; Pérez-Jorge, C.; Esteban, J.; Vallet-Regí, M. Use of anodized titanium alloy as drug carrier: Ibuprofen as model of drug releasing. Int. J. Pharm. 2015 , 492 , 207–212. [ Google Scholar ] [ CrossRef ]
• Shen, K.; Tang, Q.; Fang, X.; Zhang, C.; Zhu, Z.; Hou, Y.; Lai, M. The sustained release of dexamethasone from TiO 2 nanotubes reinforced by chitosan to enhance osteoblast function and anti-inflammation activity. Mater. Sci. Eng. C Mater. Biol. Appl. 2020 , 116 , 111241. [ Google Scholar ] [ CrossRef ]
• Luo, J.; Ding, X.; Song, W.; Bai, J.-Y.; Liu, J.; Li, Z.; Meng, F.-H.; Chen, F.-H.; Zhang, Y.-M. Inducing macrophages M2 polarization by dexamethasone laden mesoporous silica nanoparticles from titanium implant surface for enhanced osteogenesis. Acta Metall. Sin. 2019 , 32 , 1253–1260. [ Google Scholar ] [ CrossRef ]
• Wei, Y.; Liu, Z.; Zhu, X.; Jiang, L.; Shi, W.; Wang, Y.; Xu, N.; Gang, F.; Wang, X.; Zhao, L.; et al. Dual directions to address the problem of aseptic loosening via electrospun PLGA @ aspirin nanofiber coatings on titanium. Biomaterials 2020 , 257 , 120237. [ Google Scholar ] [ CrossRef ]
• You, Y.; Wang, W.; Li, Y.; Song, Y.; Jiao, J.; Wang, Y.; Chen, B.; Liu, J.; Qi, H.; Liang, Y. Aspirin/PLGA coated 3D-printed Ti-6Al-4V alloy modulate macrophage polarization to enhance osteoblast differentiation and osseointegration. J. Mater. Sci. Mater. Med. 2022 , 33 , 73. [ Google Scholar ] [ CrossRef ]
• Zhao, Q.; Zhang, Y.; Xiao, L.; Lu, H.; Ma, Y.; Liu, Q.; Wang, X. Surface engineering of titania nanotubes incorporated with double-layered extracellular vesicles to modulate inflammation and osteogenesis. Regen. Biomater. 2021 , 8 , rbab010. [ Google Scholar ] [ CrossRef ]
• Jayasree, A.; Liu, C.; Salomon, C.; Ivanovski, S.; Gulati, K.; Han, P. Microvesicle-eluting nano-engineered implants influence inflammatory response of keratinocytes. Drug. Deliv. Transl. Res. 2023 . online ahead of print . [ Google Scholar ]
• Silva, R.C.S.; Agrelli, A.; Andrade, A.N.; Mendes-Marques, C.L.; Arruda, I.R.S.; Santos, L.R.L.; Vasconcelos, N.F.; Machado, G. Titanium Dental Implants: An Overview of Applied Nanobiotechnology to Improve Biocompatibility and Prevent Infections. Materials 2022 , 15 , 3150. [ Google Scholar ] [ CrossRef ]
• Schwarz, F.; Derks, J.; Monje, A.; Wang, H.L. Peri-implantitis. J. Periodontol. 2018 , 89 , 267–290. [ Google Scholar ] [ CrossRef ]
• Berglundh, T.; Armitage, G.; Araujo, M.G.; Avila-Ortiz, G.; Blanco, J.; Camargo, P.M.; Chen, S.; Cochran, D.; Derks, J.; Figuero, E.; et al. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J. Clin. Periodontol. 2018 , 45 , 286–291. [ Google Scholar ] [ CrossRef ]
• Derks, J.; Schaller, D.; Håkansson, J.; Wennström, J.L.; Tomasi, C.; Berglundh, T. Peri-implantitis—Onset and pattern of progression. J. Clin. Periodontol. 2016 , 43 , 383–388. [ Google Scholar ] [ CrossRef ]
• Schwarz, F.; Ramanauskaite, A. It is all about peri-implant tissue health. Periodontol. 2000 2022 , 88 , 9–12. [ Google Scholar ] [ CrossRef ]
• Moraes, G.; Zambom, C.; Siqueira, W.L. Nanoparticles in Dentistry: A Comprehensive Review. Pharmaceuticals 2021 , 14 , 752. [ Google Scholar ] [ CrossRef ]
• Lagopati, N.; Efstathopoulos, E.P.; Veroutis, D.; Katifelis, H.; Theocharous, G.; Pantelis, P.; Evangelou, K.; Gorgoulis, V.G.; Gazouli, M. Hybrid Multifunctional Nanomaterials for Diagnostic and Therapeutic Applications. In Pharmaceutical Nanobiotechnology for Targeted Therapy , 1st ed.; Barabadi, H., Mostafavi, E., Saravanan, M., Eds.; Nanotechnology in the Life Sciences; Springer: Cham, Sawitzerland, 2022; pp. 489–519. [ Google Scholar ]
• Lagopati, N.; Pippa, N.; Gatou, M.-A.; Papadopoulou-Fermeli, N.; Gorgoulis, V.G.; Gazouli, M.; Pavlatou, E.A. Marine-Originated Materials and Their Potential Use in Biomedicine. Appl. Sci. 2023 , 13 , 9172. [ Google Scholar ] [ CrossRef ]
• Gatou, M.-A.; Skylla, E.; Dourou, P.; Pippa, N.; Gazouli, M.; Lagopati, N.; Pavlatou, E.A. Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications. Crystals 2024 , 14 , 215. [ Google Scholar ] [ CrossRef ]
• Puckett, S.D.; Taylor, E.; Raimondo, T.; Webster, T.J. The relationship between the nanostructure of titanium surfaces and bacterial attachment. Biomaterials 2010 , 31 , 706–713. [ Google Scholar ] [ CrossRef ]
• Cao, H.; Liu, X.; Meng, F.; Chu, P.K. Biological actions of silver nanoparticles embedded in titanium controlled by micro-galvanic effects. Biomaterials 2011 , 32 , 693–705. [ Google Scholar ] [ CrossRef ]
• Zhu, Y.; Cao, H.; Qiao, S.; Wang, M.; Gu, Y.; Luo, H.; Meng, F.; Liu, X.; Lai, H. Hierarchical micro/nanostructured titanium with balanced actions to bacterial and mammalian cells for dental implants. Int. J. Nanomed. 2015 , 10 , 6659–6674. [ Google Scholar ] [ CrossRef ]
• Lampé, I.; Beke, D.; Biri, S.; Csarnovics, I.; Csik, A.; Dombrádi, Z.; Hajdu, P.; Hegedűs, V.; Rácz, R.; Varga, I.; et al. Investigation of silver nanoparticles on titanium surface created by ion implantation technology. Int. J. Nanomed. 2019 , 14 , 4709–4721. [ Google Scholar ] [ CrossRef ]
• Liu, X.; Man, H.C. Laser fabrication of Ag-HA nanocomposites on Ti6Al4V implant for enhancing bioactivity and antibacterial capability. Mater. Sci. Eng. C Mater. Biol. Appl. 2017 , 70 , 1–8. [ Google Scholar ] [ CrossRef ]
• Gosau, M.; Haupt, M.; Thude, S.; Strowitzki, M.; Schminke, B.; Buergers, R. Antimicrobial effect and biocompatibility of novel metallic nanocrystalline implant coatings. J. Biomed. Mater. Res. B Appl. Biomater. 2016 , 104 , 1571–1579. [ Google Scholar ] [ CrossRef ]
• Hameed, H.A.; Ariffin, A.; Luddin, N.; Husein, A. Evaluation of antibacterial properties of copper nanoparticles surface coating on titanium dental implant. J. Pharm. Sci. Res. 2018 , 10 , 1157–1160. [ Google Scholar ]
• Liu, M.; Zhou, J.; Yang, Y.; Zheng, M.; Yang, J.; Tan, J. Surface modification of zirconia with polydopamine to enhance fibroblast response and decrease bacterial activity in vitro: A potential technique for soft tissue engineering applications. Colloids Surf. B Biointerfaces 2015 , 136 , 74–83. [ Google Scholar ] [ CrossRef ]
• Zhao, L.; Wang, H.; Huo, K.; Cui, L.; Zhang, W.; Ni, H.; Zhang, Y.; Wu, Z.; Chu, P.K. Antibacterial nano-structured titania coating incorporated with silver nanoparticles. Biomaterials 2011 , 32 , 5706–5716. [ Google Scholar ] [ CrossRef ]
• Huo, K.; Zhang, X.; Wang, H.; Zhao, L.; Liu, X.; Chu, P.K. Osteogenic activity and antibacterial effects on titanium surfaces modified with Zn-incorporated nanotube arrays. Biomaterials 2013 , 34 , 3467–3478. [ Google Scholar ] [ CrossRef ]
• Wang, R.; Shi, M.; Xu, F.; Qiu, Y.; Zhang, P.; Shen, K.; Zhao, Q.; Yu, J.; Zhang, Y. Graphdiyne-modified TiO 2 nanofibers with osteoinductive and enhanced photocatalytic antibacterial activities to prevent implant infection. Nat. Commun. 2020 , 11 , 4465. [ Google Scholar ] [ CrossRef ]
• Gulati, K.; Ramakrishnan, S.; Aw, M.S.; Atkins, G.J.; Findlay, D.M.; Losic, D. Biocompatible polymer coating of titania nanotube arrays for improved drug elution and osteoblast adhesion. Acta Biomater. 2012 , 8 , 449–456. [ Google Scholar ] [ CrossRef ]
• Kumeria, T.; Mon, H.; Aw, M.S.; Gulati, K.; Santos, A.; Griesser, H.J.; Losic, D. Advanced biopolymer-coated drug-releasing titania nanotubes (TNTs) implants with simultaneously enhanced osteoblast adhesion and antibacterial properties. Colloids Surf. B Biointerfaces 2015 , 130 , 255–263. [ Google Scholar ] [ CrossRef ]
• Baghdan, E.; Pinnapireddy, S.; Vögeling, H.; Schaefer, J.; Eckert, A.; Bakowsky, U. Nano spray drying: A novel technique to prepare well-defined surface coatings for medical implants. J. Drug Deliv. Sci. Technol. 2018 , 48 , 145–151. [ Google Scholar ] [ CrossRef ]
• Ma, M.; Kazemzadeh-Narbat, M.; Hui, Y.; Lu, S.; Ding, C.; Chen, D.D.; Hancock, R.E.; Wang, R. Local delivery of antimicrobial peptides using self-organized TiO 2 nanotube arrays for peri-implant infections. J. Biomed. Mater. Res. A 2012 , 100 , 278–285. [ Google Scholar ] [ CrossRef ]
• Srivastava, M.G.; Kamarudin, N.H.N.; Aktan, M.K.; Zheng, K.; Zayed, N.; Yongabi, D.; Wagner, P.; Teughels, W.; Boccaccini, A.R.; Braem, A. pH-Triggered Controlled Release of Chlorhexidine Using Chitosan-Coated Titanium Silica Composite for Dental Infection Prevention. Pharmaceutics 2024 , 16 , 377. [ Google Scholar ] [ CrossRef ]
• Cheng, Y.F.; Zhang, J.Y.; Wang, Y.B.; Li, C.M.; Lu, Z.S.; Hu, X.F.; Xu, L.Q. Deposition of catechol-functionalized chitosan and silver nanoparticles on biomedical titanium surfaces for antibacterial application. Mater. Sci. Eng. C Mater. Biol. Appl. 2019 , 98 , 649–656. [ Google Scholar ] [ CrossRef ]
• Mishra, S.K.; Ferreira, J.M.; Kannan, S. Mechanically stable antimicrobial chitosan-PVA-silver nanocomposite coatings deposited on titanium implants. Carbohydr. Polym. 2015 , 121 , 37–48. [ Google Scholar ] [ CrossRef ]
• Song, J.; Chen, Q.; Zhang, Y.; Diba, M.; Kolwijck, E.; Shao, J.; Jansen, J.A.; Yang, F.; Boccaccini, A.R.; Leeuwenburgh, S.C. Electrophoretic deposition of chitosan coatings modified with gelatin nanospheres to tune the release of antibiotics. ACS Appl. Mater. Interfaces 2016 , 8 , 13785–13792. [ Google Scholar ] [ CrossRef ]
• Choi, S.H.; Jang, Y.S.; Jang, J.H.; Bae, T.S.; Lee, S.J.; Lee, M.H. Enhanced antibacterial activity of titanium by surface modification with polydopamine and silver for dental implant application. J. Appl. Biomater. Funct. Mater. 2019 , 17 , 2280800019847067. [ Google Scholar ] [ CrossRef ]
• Palla-Rubio, B.; Araújo-Gomes, N.; Fernández-Gutiérrez, M.; Rojo, L.; Suay, J.; Gurruchaga, M.; Goñi, I. Synthesis and characterization of silica-chitosan hybrid materials as antibacterial coatings for titanium implants. Carbohydr. Polym. 2019 , 203 , 331–341. [ Google Scholar ] [ CrossRef ]
• Xu, G.; Shen, X.; Dai, L.; Ran, Q.; Ma, P.; Cai, K. Reduced bacteria adhesion on octenidine loaded mesoporous silica nanoparticles coating on titanium substrates. Mater. Sci. Eng. C Mater. Biol. Appl. 2017 , 70 , 386–395. [ Google Scholar ] [ CrossRef ]
• Li, Y.; Liu, X.; Tan, L.; Cui, Z.; Yang, X.; Yeung, K.W.K.; Pan, H.; Wu, S. Construction of N-halamine labeled silica/zinc oxide hybrid nanoparticles for enhancing antibacterial ability of Ti implants. Mater. Sci. Eng. C Mater. Biol. Appl. 2017 , 76 , 50–58. [ Google Scholar ] [ CrossRef ]
• Kulshrestha, S.; Khan, S.; Meena, R.; Singh, B.R.; Khan, A.U. A graphene/zinc oxide nanocomposite film protects dental implant surfaces against cariogenic Streptococcus mutans. Biofouling 2014 , 30 , 1281–1294. [ Google Scholar ] [ CrossRef ]
• De Leo, V.; Mattioli-Belmonte, M.; Cimmarusti, M.T.; Panniello, A.; Dicarlo, M.; Milano, F.; Agostiano, A.; De Giglio, E.; Catucci, L. Liposome-modified titanium surface: A strategy to locally deliver bioactive molecules. Colloids Surf. B Biointerfaces 2017 , 158 , 387–396. [ Google Scholar ] [ CrossRef ]
• Nagay, B.E.; Cordeiro, J.M.; Barao, V.A.R. Insight Into Corrosion of Dental Implants: From Biochemical Mechanisms to Designing Corrosion-Resistant Materials. Curr. Oral Health Rep. 2022 , 9 , 7–21. [ Google Scholar ] [ CrossRef ]
• Guo, T.; Scimeca, J.C.; Ivanovski, S.; Verron, E.; Gulati, K. Enhanced Corrosion Resistance and Local Therapy from Nano-Engineered Titanium Dental Implants. Pharmaceutics 2023 , 15 , 315. [ Google Scholar ] [ CrossRef ]
• Indira, K.; Mudali, U.K.; Rajendran, N. In-vitro biocompatibility and corrosion resistance of strontium incorporated TiO 2 nanotube arrays for orthopaedic applications. J. Biomater. Appl. 2014 , 29 , 113–129. [ Google Scholar ] [ CrossRef ]
• Al-Saady, F.; Rushdi, S.; Abbar, A. Improvement the corrosion Behavior of Titanium by Nanotubular Oxide in a simulated saliva solution. IOP Conf. Ser. Mater. Sci. Eng. 2020 , 870 , 012060. [ Google Scholar ] [ CrossRef ]
• Azari, R.; Rezaie, H.R.; Khavandi, A. Effect of titanium dioxide intermediate layer on scratch and corrosion resistance of sol-gel-derived HA coating applied on Ti-6Al-4V substrate. Prog. Biomater. 2021 , 10 , 259–269. [ Google Scholar ] [ CrossRef ]
• Shen, Y.; Fang, K.; Xiang, Y.; Xu, K.; Yu, L.; Chen, J.; Ma, P.; Cai, K.; Shen, X.; Liu, J. Improvement in osteogenesis, vascularization, and corrosion resistance of titanium with silicon-nitride doped micro-arc oxidation coatings. Front. Bioeng. Biotechnol. 2022 , 10 , 1023032. [ Google Scholar ] [ CrossRef ]
• Afrouzian, A.; Avila, J.D.; Bandyopadhyay, A. Biotribocorrosion of 3D-Printed silica-coated Ti6Al4V for load-bearing implants. J. Mater. Res. 2021 , 36 , 3974–3984. [ Google Scholar ] [ CrossRef ]
• Hsu, S.M.; Fares, C.; Xia, X.; Rasel, M.A.J.; Ketter, J.; Afonso Camargo, S.E.; Haque, M.A.; Ren, F.; Esquivel-Upshaw, J.F. In Vitro Corrosion of SiC-Coated Anodized Ti Nano-Tubular Surfaces. J. Funct. Biomater. 2021 , 12 , 52. [ Google Scholar ] [ CrossRef ]
• Harb, S.V.; Bassous, N.J.; de Souza, T.A.C.; Trentin, A.; Pulcinelli, S.H.; Santilli, C.V.; Webster, T.J.; Lobo, A.O.; Hammer, P. Hydroxyapatite and β-TCP modified PMMA-TiO 2 and PMMA-ZrO 2 coatings for bioactive corrosion protection of Ti6Al4V implants. Mater. Sci. Eng. C Mater. Biol. Appl. 2020 , 116 , 111149. [ Google Scholar ] [ CrossRef ]
• Kazemi, M.; Ahangarani, S.H.; Esmailian, M.; Shanaghi, A. Investigation on the corrosion behavior and biocompatibility of Ti-6Al-4V implant coated with HA/TiN dual layer for medical applications. Surf. Coat. Technol. 2020 , 397 , 126044. [ Google Scholar ] [ CrossRef ]
• Aydin, B.A.; Siğircik, G.; Takci, H. Antimicrobial properties and corrosion behavior of TiO 2 -NTs electrodes modified with Ag and ZnO nanorod in simulated body fluid solution. J. Mol. Struct. 2021 , 1240 , 130569. [ Google Scholar ] [ CrossRef ]
• Xia, C.; Ma, X.; Zhang, X.; Li, K.; Tan, J.; Qiao, Y.; Liu, X. Enhanced physicochemical and biological properties of C/Cu dual ions implanted medical titanium. Bioact. Mater. 2020 , 5 , 377–386. [ Google Scholar ] [ CrossRef ]
• Zheng, Y.F.; Liu, D.; Liu, X.L.; Li, L. Enhanced corrosion resistance of Zr coating on biomedical TiNi alloy prepared by plasma immersion ion implantation and deposition. Appl. Surf. Sci. 2008 , 255 , 512–514. [ Google Scholar ] [ CrossRef ]
• Yusuf, D.; Maryani, E.; Mardhian, D.F.; Noviyanti, A.R. Evaluation of Structural Stability, Mechanical Properties, and Corrosion Resistance of Magnesia Partially Stabilized Zirconia (Mg-PSZ). Molecules 2023 , 28 , 6054. [ Google Scholar ] [ CrossRef ]
• Zaher, H.; Hefnawy, M.A.; Medany, S.; Kamel, S.; Fadl-allah, S. Synergetic effect of essential oils and calcium phosphate nanoparticles for enhancement the corrosion resistance of titanium dental implant. Sci. Rep. 2024 , 14 , 1573. [ Google Scholar ] [ CrossRef ]

Click here to enlarge figure

Studies with Nanomaterials for Osseointegration Improvement
Study	Method	Nanomaterial	Result
Yang et al., 2020 [ ]	In vitro and in vivo	TNTs	Reversed overproduction of ROS, antioxidant effect
Balasundaram et al., 2007 [ ]	In vitro	TNTs loaded with BMP-2	Increased osteoblast adhesion
Kodama et al., 2009 [ ]	In vitro	TNTs loaded with synthetic HA	Enhanced BIC and apatite formation
Liu et al., 2014 [ ]	In vitro	TNTs loaded with BSA	Preservation of crestal bone, conductivity for soft tissue attachment, antibacterial properties
6Lee et al., 2011 [ ]	In vitro and In vivo	TNTs loaded with ibandronate	Higher removal torque values, increased bone density and bone formation markers expression
Shen et al., 2016 [ ]	In vitro and in vivo	TNTs and HA loaded with alendronate	In vitro inhibition of osteoclast differentiation and the improvement of osteoblast activity and in vivo early local osseointegration and mechanical fixation
Zhang et al., 2014 [ ]	In vitro and In vivo	TNTs loaded with rhPDGF-BB	Enhanced MSC adhesion, proliferation and differentiation, rapid bone formation
Lee et al., 2013 [ ]	In vivo	TNTs loaded with NAC peptide	New bone formation, excellent osseointegration
Zhang et al., 2020 [ ]	In vitro	TNTs loaded with Sr-La	Superior osseointegration ability and increased cellular functions
Lee et al., 2017 [ ]	In vitro and in vivo	Chitosan-Au NPs with PRAγ cDNA	Regional bone regeneration and improved osseointegration
Fang et al., 2014 [ ]	In vitro	Chitosan loaded with Sema 3A	Higher osteogenic gene expression and Ca apposition
Yamada et al., 2012 [ ]	In vivo	Nano-HA on microroughened implants	Increased strength at bone implant interface, higher BIC and bone volume
Zhao et al., 2011 [ ]	In vitro and in vivo	Nano-HA Mg doped	In vitro promotion of osteogenesis and in vivo improvement of osseointegration
Heo et al., 2016 [ ]	In vitro and in vivo	GNP coating	In vitro stimulated cellular responses and in vivo enhance new bone formation
Qiao et al., 2015 [ ]	In vitro and in vivo	AgNPs	Increased implant stability and enhanced bone formation
Bartkowiak et al., 2018 [ ]	In vitro	SiNPs on HA treated implants	Favorable mineralization of deposited bone matrix and accelerated bone healing
Jo et al., 2017 [ ]	In vitro and in vivo	SiNPs	Increase microroughness, osteopromotive conditions
Covarrubias et al., 2016 [ ]	In vitro and in vivo	Nanoporous silica coating loaded with bioactive glass nanoparticles (nBG/NSC) on Ti implants	Accelerate the formation of bone tissue in the periphery of the implant after 3 weeks of implantation.
Vandamme et al., 2020 [ ]	In vivo	Mesoporous SiO customization on Ti implants	Does not seem to compromise the osseointegration process.
Frankenberger et al., 2021 [ ]	In vivo	Nanocrystalline hydroxyapatite (ncHA) embedded in a silica matrix and interfacial composite layer (SPI) on PEEK implants	Higher bone to implant contact (BIC) and pull-out tests revealed higher pull-out forces.
Frandsen et al., 2011 [ ]	In vitro	Zirconia nanotubes	Enhanced cell adhesion and spreading and improved osteoblast growth
Wang et al., 2019 [ ]	In vitro	GO	Increased surface wettability and apatite formation

Studies with Nanomaterials for Immunomodulation
Study	Method	Nanomaterial	Result
Kang et al., 2010 [ ]	In vitro	PEG and BMP-2 on Ti implants	Non-biofouling and simultaneous osteoconductive properties.
Smith et al., 2013 [ ]	In vitro	TNTs	Decrease in monocyte, macrophage and neutrophil functionality and reduced stimulation of immune responses.
Neascu et al., 2015 [ ]	In vitro	TNTs	Suppression of MAPK and NF-κB pathways, potential mechanism for anti-inflammatory activity.
Gulati et al., 2018 [ ]	In vitro	nanopores	Reduced proliferation of macrophages, increased osteoblast and fibroblast activity.
Li et al., 2023 [ ]	In vitro	TiO nanoarrays with different morphologies in titanium.	TiO nanorods with a larger diameter promotes osteogenic differentiation of BMSCs and stimulates macrophage polarization to M2 generating an immune microenvironment.
Su et al., 2020 [ ]	In vitro	Graphene oxide (GO) coating in titanium surfaces	Manipulate the polarization of macrophages and the expression of inflammatory cytokines. lmmunomodulatory effects in osteogenesis.
Li et al., 2020 [ ]	In vitro	Thermo-sensitive hydrogel on anodized Ti surfaces	Macrophages polarize toward the M2 phenotype, promotes tissue repair and osteoblast differentiation.
Chen et al., 2022 [ ]	In vitro	Curcumin loaded through polydopamine (PDA) onto copper-bearing titanium alloy (Cu-Ti)	Immune regulation of macrophages through regulation of their polar differentiation.
Liu et al., 2024 [ ]	In vitro and in vivo	Metal phenolic nanocoating consisting of tannic acid and strontium on Ti substrates	Antioxidant properties, accelerated osteogenic differentiation, inhibition of inflammatory responses.
Doadrio et al., 2015 [ ]	In vitro	TNTs and ibuprofen	Confirmation of the ability of TNTs to act as an intelligent nanomaterial
Shen et al., 2020 [ ]	In vitro	TNT-Cht and DEX	Enhanced proliferation and differentiation of osteoblasts, suppressed production of nitric oxide (NO) and pro-inflammatory cytokines from macrophages.
Luo et al., 2019 [ ]	In vitro	MSNs + DEX	M2-polarization of macrophages, favorable osteogenesis but dose dependent toxicity.
Wei et al., 2020 [ ]	In vitro and in vivo	PLGA nanofibers loaded with aspirin	In vitro inhibition of M1 polarization and increased proliferation and differentiation of MSCs to osteoblasts, in vivo enhanced osseointegration.
You et al., 2022 [ ]	In vitro and in vivo	PLGA loaded with aspirin in 3D printed Ti alloy implants	In vitro enhanced M2 gene and protein expression and in vivo superior osseointegration.
Zhao et al., 2021 [ ]	In vitro	Double layer customization on TNTs Internal layer: MSC-derived exosomes on polydopamine External layer: 3-day differentiated MSC-derived exosomes on hydrogel	Enhances the migration and osteogenic differentiation of hBMSCs. Modulation of macrophage polarization.
Jayasree et al., 2023 [ ]	In vitro	TNTs loaded with microvessels (MVs)	Controlled local release pattern for up to 7 days. Reduction in the production of pro-inflammatory cytokines in keratinocytes.

Studies with Nanomaterials for the Prevention of Peri-Implantitis
Study	Method	Nanomaterial	Result
Puckett et al., 2010 [ ]	In vitro	Nanorough Ti surfaces from electron beam evaporation	Decreased bacterial adhesion especially of S. aureus, S. epidermidis and P. aeruginosa.
Cao et al., 2011 [ ]	In vitro	AgNPs	Inhibition of S. aureus and E. coli growth and enhanced antibacterial activity of the surface due to micro galvanic effects. The amounts of S. aureus and E. coli on 0.5h-Ag-PIII are reduced by approximately 93% and 95% after 24 h.
Zhu et al., 2015 [ ]	In vitro	AgNPs	Anti-bacterial activity against gram-positive S. aureus and gram-negative F. nucleatum. The antibacterial activity of Ag NPs against F. nucleatum was superior to S. aureus.
Lampé et al., 2019 [ ]	In vitro	AgNPs	64.6% of antibacterial effect was noted for the nanoparticle-covered samples.
Liu et al., 2017 [ ]	In vitro	AgNPs contained in HA	Bacterial inhibition for percentage of 2% silver.
Gosau et al., 2015 [ ]	In vitro	Nanocrystalline Ag, Cu and Bis coating	Favorable anti-bacterial effects, but cytotoxicity for Cu.
Hameed et al., 2018 [ ]	In vitro	CuNPs	Enhanced antibacterial effect against P. gingivalis.
Liu et al., 2015 [ ]	In vitro	Polydopamine (PDA) coated zirconia	Increased cell adhesion and proliferation. The number of adherent bacteria decreased significantly on zirconia after PDA coating. The PDA coated zirconia showed both lower percentages of S. gordonii (0.91 ± 0.16%) and S. mutans (1.85 ± 0.48%) than the pristine zirconia (1.73 ± 0.32% and 3.06 ± 0.47%) (p < 0.01).
Zhao et al., 2011 [ ]	In vitro	TNTs loaded with AgNPs	TNTs kill planktonic bacteria for the first days after surgery and inhibit bacterial adhesion for 30 days.
Huo et al., 2013 [ ]	In vitro	TNTs loaded with Zn	Good intrinsic antibacterial properties with simultaneous favorable soft and hard tissue integration.
Wang et al., 2020 [ ]	In vitro and in vivo	graphdiyne (GDY) composite TiO nanofiber coating	Increased photocatalysis and prolonged antibacterial ability, especially against methicillin-resistant staphylococcus aureus (MRSA). ROS release from this system prevented the formation of biofilm. In standard plate counting assay tests, the number of colonies of the TiO /GDY + UV group reduced by 98% compared to that of the group not treated with UV
Gulati et al., 2012 [ ]	In vitro	TNTs loaded with indomethacin and covered by chitosan/PLGA	Extended drug release properties, favorable bone cell adhesion and improved anti-bacterial properties.
Kumeria et al., 2015 [ ]	In vitro	TNTs decorated with micelles loaded with gentamicin and covered by chitosan/PLGA	Long term and improved anti-bacterial properties, prevention of biofilm formation.
Baghdan et al., 2022 [ ]	In vitro	PLGA loaded with norfloxacin on Ti discs	Up to 99.83% reduction in the number of viable bacterial colonies.
Ma et al., 2011 [ ]	In vitro	TNTs loaded with AMPs	Reduction of gram-positive bacterium S. aureus levels and inhibition of bacterial adhesion on the implant surface. In survival assay tests, AMP loaded TNTs demonstrated bacterial killing with approximately 99.9% decrease. About 200-fold decrease of bacterial colonies was observed for the peptide-loaded groups compared with the groups without peptide.
Srivastava et al., 2024 [ ]	In vitro	Macroporous Ti matrix is filled with mesoporous silica, coated with crosslinked chitosan releasing CHX	reduced numbers of bacterial growth compared to the uncoated Ti/SiO sample (S. sobrinus, F. nucleatum)
Cheng et al., 2019 [ ]	In vitro	AgNPs on catechol-containing chitosan (CACS) coatings	Anti-bacterial properties of the system, both against gram-positive and gram-negative bacteria.
Mishra et al., 2017 [ ]	In vitro	Cht-PVA-Silver nanocomposite coating	Better functional properties and enhanced bactericidal activity against S. aureus and E. coli.
Song et al., 2016 [ ]	In vitro	Gelatin nanospheres loaded with antibiotics and encapsulated in chitosan matrix	Inhibition of bacterial growth. In inhibition zone tests the samples that contained moxifloxacin with or without gelatin nanospheres displayed an obvious inhibition zone whereas none of the groups with or without vancomycin induced the formation of an inhibition zone.
Choi et al., 2019 [ ]	In vitro	AgNPs on PDA	Less bacteria colonization in Ag/PDA treated implants when compared with uncoated titanium surfaces, bacterial growth was found retarded in bacterial growth curves for S. mutans and P. gingivalis.
Palla-Rubio et al., 2019 [ ]	In vitro	Silica—chitosan coating on Ti implants	Coatings with 5% and 10% of chitosan have particularly good bactericidal properties.
Xu et al., 2017 [ ]	In vitro	MSNs loaded with OCT	Inhibition of bacterial adhesion was noted, especially for S. mutans and E. coli. The antibacterial ratios of S. aureus and E. coli were 21.5 ± 6.2% and 13.1 ± 4.8%, and 97.1 ± 0.8% and 86.3 ± 1.2%, in respect to MAO/Si substrates and MAO/Si/OCT substrates, respectively.
Li et al., 2017 [ ]	In vitro	PSA nanoparticles, zinc oxide (ZnO) covered by a silica film on the outside and N-halamine polymer labeling	Excellent anti-bacterial activity against P. aeruginosa, E. coli and S. aureus with no obvious cytotoxicity.
Kulshrestha et al., 2014 [ ]	In vitro	Graphene ZnO coating	Reduction in biofilm deposition.
De Leo et al., 2017 [ ]	In vitro	Liposome coatings	The system can be utilized for the incorporation of various moieties with different polarities such as an antibiotics, anti-inflammatory drugs and protein like growth factors.

Studies with Nanomaterials for Corrosion Resistance
Study	Method	Nanomaterial	Result
Indira et al., 2004 [ ]	In vitro	ZrNPs loaded in TNTs	Enhanced corrosion resistance.
Al-Saady et al., 2023 [ ]	In vitro	Titanium oxide nanotubes	Enhanced corrosion resistance.
Azari et al., 2023 [ ]	In vitro	HA coating with intermediateTiO layer on Ti6Al4V substrates	Intermediate layer reduces the corrosion current by 65 percent and improves the corrosion resistance of monolayer HA-coated Ti-6Al-4 V alloy.
Shen et al., 2022 [ ]	In vitro	Silicon nitride (Si N ) nanoparticles	Corrosion tendency and corrosion rate of Si3N4-doped specimens were significantly reduced, with Si N concentration dependence.
Afrouzian et al., 2021 [ ]	In vitro	Silica coating (SiO ) on the surface of Ti6Al4V alloy via 3D printing	Promising tribological performance.
Hsu et al., 2021 [ ]	In vitro	Silicon carbide (SiC) on titanium dioxide nanotubes (ATO)	Improved corrosion resistance.
Harb et al., 2020 [ ]	In vitro	PMMA-TiO and PMMA-ZrO nanocomposite coatings with calcium phosphates in Ti Al V implants	Excellent corrosion resistance in SBF solution. PMMA-TiO -βTCP coating presented low frequency impedance modulus of 430 GΩ cm unchanged for 21 days. (>100 GΩ cm in coatings indicate very good anticorrosion protection).
Kazemi et al., 2020 [ ]	In vitro	Titanium Nitride (TiN)-HA multilayer composite in Ti Al V implants	Lowest corrosion current density and highest corrosion potential.
Aydin et al., 2021 [ ]	In vitro	TiO nanotubes modifies with ZnO nanorods and AgNPs	ZnO-TiO nanotubes exhibited high resistance value at immersion of 7 days.
Xia et al., 2020 [ ]	In vitro	C/Cu NPs	Improved mechanical properties and reduction of free copper ions. The Cu ion release was regulated by the galvanic corrosion effect of the system, with no additional cytotoxicity induced.
Zheng et al., 2008 [ ]	In vitro	Zr coating in TiNi alloy implant	Reduced Ni ion release and improved corrosion resistance was noted for Zr coated substrates.
Yusuf et al., 2023 [ ]	In vitro	Nano Mg-PSZ partially stabilized zirconia	The greater the concentration of magnesia (MgO) in doping the ZrO , the greater the degradation resistance of Mg-PSZ in simulated body fluid (SBF) solution.
Zaher et al., 2024 [ ]	In vitro	Amorphous calcium phosphate nanoparticles (ACP-NPs) in Ti bare	Increased corrosion resistance.

The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

Marasli, C.; Katifelis, H.; Gazouli, M.; Lagopati, N. Nano-Based Approaches in Surface Modifications of Dental Implants: A Literature Review. Molecules 2024 , 29 , 3061. https://doi.org/10.3390/molecules29133061

Marasli C, Katifelis H, Gazouli M, Lagopati N. Nano-Based Approaches in Surface Modifications of Dental Implants: A Literature Review. Molecules . 2024; 29(13):3061. https://doi.org/10.3390/molecules29133061

Marasli, Chrysa, Hector Katifelis, Maria Gazouli, and Nefeli Lagopati. 2024. "Nano-Based Approaches in Surface Modifications of Dental Implants: A Literature Review" Molecules 29, no. 13: 3061. https://doi.org/10.3390/molecules29133061

Article Metrics

Article access statistics, further information, mdpi initiatives, follow mdpi.

Subscribe to receive issue release notifications and newsletters from MDPI journals

Observation of the failure mechanism in Ag 10 Ge 15 Te 75 -based memristor induced by ion transport

• Yuwei Xiong

Porous block copolymer films with self-adjustable optical transmittance and passive radiative cooling

• Weiming Tang
• Mingjie Liu

Facile synthesis of intra-nanogap enhanced Raman tags with different shapes

• Brian T. Scarpitti
• Zachary D. Schultz

Fabricating bio-inspired high impact resistance carbon nanotube network films for multi-protection under an extreme environment

• Mingquan Zhu
• Zhong Zhang

Boosting oxygen reduction in acidic media through integration of Pt-Co alloy effect and strong interaction with carbon defects

• Haoyun Sheng

Erratum to: Polymer electrolytes for flexible zinc-air batteries: Recent progress and future directions

• Xian Jun Loh

Yolk–shell FeCu/NC electrocatalyst boosting high-performance zinc-air battery

• Tianyu Zhang
• Junfeng Liu

Self-assembled all-oxides three-phase vertically aligned nanocomposite thin film with multifunctionality

• Jijie Huang
• Haiyan Wang

Research progress in performance improvement strategies and sulfur conversion mechanisms of Li-S batteries based on Fe series nanomaterials

• Ziyang Huang
• Zhenghua Wang

Electrical control of excitonic oscillator strength and spatial distribution in a monolayer semiconductor

• Yanming Wang
• Junrong Zhang
• Junyong Wang

Revealing the role of electrode potential micro-environments in single Mn atoms for carbon dioxide and oxygen electrolysis

• Pengcheng Liu

Microfluidic synthesis of hollow CsPbBr 3 perovskite nanocrystals through the nanoscale Kirkendall effect

• Xiaoyu Zhang
• Xiangxing Xu

Synergy enhancement of Co single atoms and asymmetric subnanoclusters for Fenton-like activation

• Wenxing Chen

Covalent triazine frameworks materials for photo- and electro-catalysis

LPA 1 antagonist-derived LNPs deliver A20 mRNA and promote anti-fibrotic activities

• Jingyue Yan
• Diana D. Kang
• Yizhou Dong

Synergistic effect and heterointerface engineering of cobalt/carbon nanotubes enhancing electromagnetic wave absorbing properties of silicon carbide fibers

• Zixiang Zhao
• Zheyipei Ma

Flurbiprofen microneedle patches for the management of acute postoperative pain

• Huaqing Chu
• Yanyan Zhang

The structure–activity relationships of Rh/CeO 2 –ZrO 2 catalysts based on Rh metal size effect in the three-way catalytic reactions

• Dongming Chen
• Weixin Zhao
• Xiaowei Huang

Chirality transfer induced circularly polarized luminescence of achiral dye molecules by plasmonic nanohelicoid

• ChunLian Zhan
• Jianzhong Zheng

Naked-eye visualization of lymph nodes using fluorescence nanoprobes in non-human primate-animal models

• Xiaoyuan Ji

MCP-1 and IL-4 encapsulated hydrogel particles with macrophages enrichment and polarization capabilities for systemic lupus erythematosus treatment

• Shengjie Zhu
• Danqing Huang
• Lingyun Sun

Visualizing the crystallization of sodium chloride under supersaturated condition

Enhanced boron neutron capture therapy (BNCT) through controlled drug release via boron-loaded nanofiber mats

• Wenyong Huang
• Yongjin Yang
• Yubin Huang

Effects of length alteration of OPE-containing mono- and dinuclear alkynylplatinum(II) terpyridine complexes on photophysical, structural and morphological properties

• Jason Koon-Lam Poon
• Sammual Yu-Lut Leung
• Vivian Wing-Wah Yam

Platelet-based bioactive systems guided precision targeting and immune regulation for cancer therapy

Interstitial carbon induces enriched Cu δ + sites in Cu 2 O nanoparticles to facilitate CO 2 electroreduction to C 2+ products

• Haoran Wang

Room-temperature and atmospheric-pressure hydrogenation of lignin-derived phenol to KA oil by Pt/NiO@MOFs

• Fengbin Zheng

Unlocking high-efficiency oxygen evolution reaction through Co-N coordination engineering in Co@N-doped porous carbon core—shell nanoparticles

• Shucheng Liu

Thermal transports in the MXenes family: Opportunities and challenges

• Xinwei Wang

A thermo-responsive rewritable plasmonic bio-memory by regulating single core-satellite gold nanocluster dissociation

Piezoelectric film promotes skin wound healing with enhanced collagen deposition and vessels regeneration via upregulation of PI3K/AKT

Single-atom Ni-N 4 for enhanced electrochemical sensing

• Fu-Zhen Xuan

Oxygen vacancy promoting artificial atom (RuPd) by d-orbital coupling for efficient water dissociation

• Ruofan Shen

Unveiling structural evolution of Fe single atom catalyst in nitrate reduction for enhanced electrocatalytic ammonia synthesis

• Xusheng Cheng
• Wenzhe Shang

Engineering S-scheme W 18 O 49 /ZnIn 2 S 4 heterojunction by Co x P nanoclusters for enhanced charge transfer capability and solar hydrogen evolution

• Xiaojie Liu
• Jianmin Dou

Low cost and low density chloride solid electrolyte for all solid state cathode with high active material ratio

• Hao-Yuan Tan
• Mei-Yu Zhou
• Hong-Bin Yao

Flat Zn deposition at battery anode via an ultrathin robust interlayer

• Yizhou Wang
• Jianyu Chen
• Husam N. Alshareef

Terpyridine-based metallo-cuboctahedron nanomaterials for efficient photocatalytic degradation of persistent organic pollutants

A single atom photocatalyst co-doped with potassium and gallium for enhancing photocatalytic hydrogen peroxide synthesis

• Yuichiro Tanaka
• Teruhisa Ohno

Wafer-scale carbon-based CMOS PDK compatible with silicon-based VLSI design flow

• Minghui Yin
• Zhiqiang Li

Fasn involved in the nephrotoxicity induced by polystyrene nanoplastics and the intervention of melatonin through intestinal microbiota-mediated lipid metabolism disorder

• Huiwen Kang
• Danyang Huang

High temperature polyimide nanocomposites containing two-dimensional nanofillers for improved thermal stability and capacitive energy storage performance

• Guanglei Wu

Mn-modified nitrogen-doped Pt-based electrocatalyst for efficient oxygen reduction in aluminum-air batteries

• Chaoquan Hu

Strong and tough chitin hydrogel constructed by dehydration and rehydration strategy

• Rui-Rui Liu
• Shu-Hong Yu

Spin chiral anisotropy of diamagnetic chiral mesostructured In 2 O 3 films

• Quanzheng Deng
• Yingying Duan

Triboelectric nanogenerators for self-powered neurostimulation

• Farid Manshaii

A passive, reusable, and resonating wearable sensing system for on-demand, non-invasive, and wireless molecular stress biomarker detection

• Shingirirai Chakoma
• Xiaochang Pei
• Rahim Esfandyarpour

Synergy effect of regulated Li-plating and functional solid electrolyte interphase on graphite anodes

• Panpan Wang
• Jianling Li

Enhancing electrochemical capacity and interfacial stability of lithium-ion batteries through side reaction modulation with ultrathin carbon nanotube film and optimized lithium cobalt oxide particle size

• Xiaogang Xia

Viral and nonviral nanocarriers for in vivo CRISPR-based gene editing

• Zhongyuan Guo
• Audrey T. Zhu
• Liangfang Zhang

• Find a journal
• Publish with us
• Track your research

• MyU : For Students, Faculty, and Staff

Four new CSE department heads begin in 2024-25

They bring a wealth of academic, research, and leadership abilities

MINNEAPOLIS / ST. PAUL (07/01/2024)—University of Minnesota College of Science and Engineering Dean Andrew Alleyne has named four new department heads in the college. All bring a wealth of academic, research, and leadership abilities to their departments.

Department of Chemical Engineering and Materials Science

Professor Kevin Dorfman has been appointed as the new d epartment h ead for the Department of Chemical Engineering and Materials Science (CEMS). Dorfman started his five-year term on July 1, 2024.

Dorfman joined the University of Minnesota faculty in January of 2006 and was quickly promoted up the ranks, receiving tenure in 2011, promotion to professor in 2015, and named a Distinguished McKnight Professor in 2020. He previously served as the director of undergraduate studies in chemical engineering from 2018-2022, where he headed a large-scale revision of the chemical engineering curriculum and saw the department through its most recent ABET accreditation. 

His research focuses on polymer physics and microfluidics, with applications in self-assembly and biotechnology. He is particularly well known for his integrated experimental and computational work on DNA confinement in nanochannels and its application towards genome mapping. Dorfman’s research has been recognized by numerous national awards including the AIChE Colburn Award, Packard Fellowship in Science and Engineering, NSF CAREER Award, and DARPA Young Faculty Award.

Dorfman received a bachelor’s degree in chemical engineering from Penn State and a master’s and Ph.D. in chemical engineering from MIT. 

Department of Industrial and Systems Engineering

Professor Archis  Ghate has been appointed as the new Department Head for the Department of Industrial and Systems Engineering after a national search. Ghate will begin his five-year term on July 8, 2024. 

Ghate is an expert in operations research and most recently served as the Fluor Endowed Chair in the Department of Industrial Engineering at Clemson University. Previously, he was a professor of industrial and systems engineering at the University of Washington. He has won several research and teaching awards, including an NSF CAREER Award. 

Ghate’s research in optimization spans areas as varied as health care, transportation and logistics, manufacturing, economics, and business analytics. He also served as a principal research scientist at Amazon working on supply chain optimization technologies. 

Ghate received bachelor’s and master’s degrees, both in chemical engineering, from the Indian Institute of Technology. He also received a master’s degree in management science and engineering from Stanford University and a Ph.D. in industrial and operations engineering from the University of Michigan.

Department of Mechanical Engineering

Professor Chris Hogan has been appointed as the new department head for the Department of Mechanical Engineering. Hogan started his five-year term on July 1, 2024.

Hogan, who currently holds the Carl and Janet Kuhrmeyer Chair, joined the University of Minnesota in 2009, and since then has taught fluid mechanics and heat transfer to nearly 1,000 undergraduates, advised 25+ Ph.D. students and postdoctoral associates, and served as the department’s director of graduate studies from 2015-2020. He most recently served as associate department head. 

He is a leading expert in particle science with applications including supersonic-to-hypersonic particle impacts with surfaces, condensation and coagulation, agricultural sprays, and virus aerosol sampling and control technologies. He has authored and co-authored more than 160 papers on these topics. He currently serves as the editor-in-chief of the Journal of Aerosol Science . Hogan received the University of Minnesota College of Science and Engineering’s George W. Taylor Award for Distinguished Research in 2023.

Hogan holds a bachelor’s degree Cornell University and a Ph.D. from Washington University in Saint Louis.

School of Physics and Astronomy

Professor James Kakalios   has been appointed   as the new department head for the School of Physics and Astronomy. Kakalios started his five-year term on July 1, 2024.

Since joining the School of Physics and Astronomy in 1988, Kakalios has built a research program in experimental condensed matter physics, with particular emphasis on complex and disordered systems. His research ranges from the nano to the neuro with experimental investigations of the electronic and optical properties of nanostructured semiconductors and fluctuation phenomena in neurological systems.

During his time at the University of Minnesota, Kakalios has served as both director of undergraduate studies and director of graduate studies. He has received numerous awards and professorships including the University’s Taylor Distinguished Professorship, Andrew Gemant Award from the American Institute of Physics, and the Award for Public Engagement with Science from the American Association for the Advancement of Science (AAAS). He is a fellow of both the American Physical Society and AAAS. 

In addition to numerous research publications, Kakalios is the author of three popular science books— The Physics of Superheroes , The Amazing Story of Quantum Mechanics , and The Physics of Everyday Things .

Kaklios received a bachelor’s degree from City College of New York and master’s and Ph.D. degrees from the University of Chicago.

Rhonda Zurn, College of Science and Engineering,  [email protected]

University Public Relations,  [email protected]

Read more stories:

Find more news and feature stories on the  CSE news page .

Related news releases

• Faculty and grad student earn collegiate awards in 2024
• U of M Professor Vladimir Sverak elected to the Academy of Arts and Sciences
• Five CSE faculty members named Distinguished McKnight University Professors
• CSE Professor Hubert Lim named director of Bakken Medical Devices Center
• Assistant Professor Zhen Liu receives prestigious Sloan Research Fellowship for early-career researchers
• Future undergraduate students
• Future transfer students
• Future graduate students
• Future international students
• Diversity and Inclusion Opportunities
• Learn abroad
• Living Learning Communities
• Mentor programs
• Programs for women
• Student groups
• Visit, Apply & Next Steps
• Information for current students
• Departments and majors overview
• Departments
• Undergraduate majors
• Graduate programs
• Integrated Degree Programs
• Additional degree-granting programs
• Online learning
• Academic Advising overview
• Academic Advising FAQ
• Academic Advising Blog
• Appointments and drop-ins
• Academic support
• Commencement
• Four-year plans
• Honors advising
• Policies, procedures, and forms
• Career Services overview
• Resumes and cover letters
• Jobs and internships
• Interviews and job offers
• CSE Career Fair
• Major and career exploration
• Graduate school
• Collegiate Life overview
• Scholarships
• Diversity & Inclusivity Alliance
• Anderson Student Innovation Labs
• Information for alumni
• Get engaged with CSE
• Upcoming events
• CSE Alumni Society Board
• Alumni volunteer interest form
• Golden Medallion Society Reunion
• 50-Year Reunion
• Alumni honors and awards
• Outstanding Achievement
• Alumni Service
• Distinguished Leadership
• Honorary Doctorate Degrees
• Nobel Laureates
• Alumni resources
• Alumni career resources
• Alumni news outlets
• CSE branded clothing
• International alumni resources
• Inventing Tomorrow magazine
• Update your info
• CSE giving overview
• Why give to CSE?
• College priorities
• Give online now
• External relations
• Giving priorities
• CSE Dean's Club
• Donor stories
• Impact of giving
• Ways to give to CSE
• Matching gifts
• CSE directories
• Invest in your company and the future
• Recruit our students
• Connect with researchers
• K-12 initiatives
• Diversity initiatives
• Research news
• Give to CSE
• CSE priorities
• Corporate relations
• Information for faculty and staff
• Administrative offices overview
• Office of the Dean
• Academic affairs
• Finance and Operations
• Communications
• Human resources
• Undergraduate programs and student services
• CSE Committees
• CSE policies overview
• Academic policies
• Faculty hiring and tenure policies
• Finance policies and information
• Graduate education policies
• Human resources policies
• Research policies
• Research overview
• Research centers and facilities
• Research proposal submission process
• Research safety
• Award-winning CSE faculty
• National academies
• University awards
• Honorary professorships
• Collegiate awards
• Other CSE honors and awards
• Staff awards
• Performance Management Process
• Work. With Flexibility in CSE
• K-12 outreach overview
• Summer camps
• Outreach events
• Enrichment programs
• Field trips and tours
• CSE K-12 Virtual Classroom Resources
• Educator development
• Sponsor an event

• Registration Log In

Journal of Nano Research Vol. 70

https://doi.org/10.4028/www.scientific.net/JNanoR.70

Table of Contents

Paper Title Page

Showing 1 to 10 of 10 Paper Titles

• For Libraries
• For Publication
• Policy & Ethics
• Privacy Policy
• All Conferences
• All Special Issues
• Read & Publish Agreements

Scientific.Net is a registered brand of Trans Tech Publications Ltd © 2024 by Trans Tech Publications Ltd. All Rights Reserved

Journal of Nano Research Impact Factor & Key Scientometrics

Journal of nano research overview, impact factor, i. basic journal info, journal issn: 16619897, 16625250, publisher: trans tech publications ltd., history: 2008-ongoing, journal hompage: link, how to get published:, research categories, scope/description:, ii. science citation report (scr), journal of nano research scr impact factor, journal of nano research scr journal ranking, journal of nano research scimago sjr rank, journal of nano research scopus 2-year impact factor trend, journal of nano research scopus 3-year impact factor trend, journal of nano research scopus 4-year impact factor trend, journal of nano research impact factor history, iii. other science influence indicators, journal of nano research h-index, journal of nano research h-index history.